Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Gurumeenakshi, G.
- Effect of High Performance Inulin (Fructo Oligosacharride) on Glycemic Control in Alloxan Induced Diabetic Rats
Abstract Views :268 |
PDF Views:1
Authors
Affiliations
1 Krishi Vigyan Kendra (T.N.A.U.), Dharmapuri (T.N.), IN
2 Home Science College and Research Institute, Tamil Nadu Agricultural University, Madurai (T.N.), IN
3 PHTC, Tamil Nadu Agricultural University, Coimbatore (T.N.), IN
4 Krishi Vigyan Kendra (T.N.A.U.), Thiruvarur (T.N.), IN
1 Krishi Vigyan Kendra (T.N.A.U.), Dharmapuri (T.N.), IN
2 Home Science College and Research Institute, Tamil Nadu Agricultural University, Madurai (T.N.), IN
3 PHTC, Tamil Nadu Agricultural University, Coimbatore (T.N.), IN
4 Krishi Vigyan Kendra (T.N.A.U.), Thiruvarur (T.N.), IN
Source
International Journal of Medical Sciences, Vol 9, No 2 (2016), Pagination: 74-80Abstract
The purpose of this study was to carried out to investigate the effect of inulin extracted from Jerusalem artichoke(Helianthus tuberosis)on decrease the blood glucose in alloxan induced diabetic rats. The oral administration of inulin decreased blood glucose , implying the utility of inulin as a bioactive material to prevent metabolic diseases oh humans. In the experiment, a total of 60 white rats were completely randomly allocated into 10 groups and six rats were used in each group (54 diabetic rats and six normal rats) were used. Diabetes was induced three days before starting the experiment. Concerning growth performance, in comparison with the control group, daily weight gain in the inulin administrated rats increased and recovered to the normal level. The average weight gain in treated group ranged from 19 g (T1) to 36g (T2I) after 28 days of study period. Blood glucose was significantly lowered in the inulin administrated group from 204.16 ± 3.57 to 121.16 ± 3.4 mg/dL (a reduction of 40.65%) at the end of four weeks feeding trials.Keywords
Inulin, Glycemic Index, Diabetic Rats.
References
- Abrams, J.J., Ginsberg, H. and. Grundy, S.M. (1982). Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus. Diabetes, 31: 903-910.
- Al-shamaony, L., Al-Khazraji, S.M. and Twaiji, H.A. (1994). Hypoglycemic effect of Artemisia herba alba II. Effect of a valuable extract on some blood parameters in diabetic animals. J.Ethno Pharma., 43 : 167-171.
- Bajpai, P.K. and Bajpai, P. (1991). Cultivation and utilization of Jerusalem artichoke for ethanol, single cell protein and high fructose syrup production. Eng. Microbial. Technol., 13: 359-362.
- Champman, V.J. and Champan, D.J. (1980). Seaweeds and their uses. Champan and Hall, London, ISBN-10:0412157403,
- Chandalia, M.S., Dokkum, V., Wezendonk, B. and Vanden Heuvel (2000). Effect of nondigestable oligo sacharrides on large – bowel function, blood lipid concentrations and glucose absorption in young healthy male subjects. Euro. J. C. Nutr., 69(1): 64-69.
- Chen, W.J.L., Anderson, J.W. and Jennings, D. (1984). Propionate may mediate the hypocholesterolemic effects of certain soluble plant fibre in cholesterol fed-rats. Proc. Soc. Exp. Biol. Med., 175 : 215-218.
- Fiordaliso, M.F., Kok, N., Desager, J.P., Goethals, F., Deboyser, D., Roberfroid, M. and Delzenne, N. (1995). Dietary oligofructose lowers triglycerides, phospholipids and cholesterol in serum and very low density lipoproteins of rats. Lipids, 30 : 163-167.
- Frank, A. (2002). Technological functionality of inulin and oligofructose. Brit. J. Nutr., 87(2): 287-291.
- Franz, M.J. (2008). Medical nutrition therapy for diabetes mellitus and hypoglycemia of nondiabetic origin. Krause’ Food and Nutrition Therapy.12th Ed. 782 pp.
- Ivana, S. (2010). HPLC Determination of Inulin in Plant Materials. Acta Chimica Slovaca, 3 : 122-129.
- Jenkins, D.J., Wolever, T.M., Vuksan, V., Brighenti, F., Cunnane, S.C., Rao, A.V., Jenkins, A.L., Buckley, G., Patten, R., Singer, W., Corey, P. and Josse, R.G. (1989). Nibbling versus gorging: metabolic advantages of increased meal frequency. New Engl. J. Med., 321 : 929-934.
- Jenkins, D.J., Wolever, T.M., Rao, A.V., Hegele, R.A., Mitchell, S.J., Ransom, T.P., Boctor, D.L., Spadafora, P.J., Jenkins. A.L. and Mehling, C. (1993). Effect on blood lipids of very high intakes of fibre in diets low in saturated fat and cholesterol. New Engl. J. Med., 329 : 21-26.
- Jerums, G.S., Panagiotopoulos, J., Forbes, T., Osicka and Cooper, M. (2003). Evolving concepts in advanced glycation, diabetic nephropathy and diabetic vascular disease. Arch. Biochem. Biophys., 419 : 55-62.
- McGowan, M.W., Joseph, D.R., Strandberg, D.R.and Zak, B.A. (1983). peroxidase coupled method for the colorimetric determination of serum triglycerides. Clin. Chem.. 29 : 538- 542.
- Murphy, O. (2001). Non-polyol low digestible carbohydrates: food applications and functional benefits. British J. Nutr., 85 (1) : 47- 53.
- Nayak, S.K., Sangeetha, N., Arora, S. and Sangwan, R.B. (2010). Functional and nutritional benefits of dietary fibre in foods. Bever. & Food World, 33(7) : 31-34.
- Roberfroid, M., Gibson, G.R. and Delzenne, N. (1993). The biochemistry of oligofructose a nondigestible fiber: an approach to calculate its caloric value. Nutr. Rev., 51:137-146.
- Rumessen, J.J., Bode, S., Hamberg, O. and Gudmand, H.E. (1990). Fructans of Jerusalem artichoke; Intestinal transport, absorption, fermentation and influence on blood glucose, insulin and C-peptide response in healthy subjects. Am. J. Clin. Nutr., 52 : 675-682.
- Silva, R. (1996). Use of inulin as a natural texture modifier. Cere. Foo. World, 10 : 792-795.
- Steinberg, H.O., Chaker, H., Leaming, R., Johnson, A., Brechtel, G. and Baron, A.D. (1996). Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J.Clinc. Invest., 97 : 291-297.
- Swain, J.F., Rouse, I.L., Curley, C.B. and Sacks, F.M. (1990). Comparison of the effects of oat bran and low fibre wheat on serum lipoprotein levels and blood pressure. New Engl. J. Med., 322 : 147-152.
- Treadway,J.L., Mendys, P. and Hoover, D.J. (2001). Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus. Expert. Opin. Investig. Drugs, 10:439-454.
- Van Loo, J., Coussement, P., de Leenheer, L., Hoebregs, H. and Smits, G. (1995). On the presence of inulin and oligofructose as natural ingredients in the western diet. Critc. Rev. Food Sci Nutr., 35 : 525-552.
- WolfI, Sadetzki, Catane, R.C., Karasik, A. and Kaufman, B. (2005). Diabetes mellitus and breast cancer. Lancet On.Col., 6: 103-111.
- Tungland, B.C. (2000). Inulin - a comprehensive scientific review. http: inulin_review.html.