T. Devasena ¹, S. Lalitha ², K. Padma ³

Affiliations
1 Department of Biotechnology, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, IN
2 Department of Obstetrics and Gynaecology, University of Michigan, Michigan, US
3 Department of Paediatrics, Raja Muthaiah Medical College Hospital, Annamalai University, Tamil Nadu, IN

Abstract

Anaemia affects more than 3.5 billion people in developing world in spite of several intervention programmes in which iron tablets are given to children, Anaemia is caused by significant changes in hematological parameters such as Red Blood Cell (RBC) count, haemoglobin, hematocrit, White Blood Cell (WBC) count and Erythrocyte Sedimentation Rate (ESR) which could be used as biomarkers in assessing the severity of several diseases including kidney diseases.

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T. Devasena ¹, S. Lalitha ², K. Padma ³

Affiliations
1 Department of Biochemistry, Annamalai University - 608 002, IN
2 Department of Obstetric and Gynaecology, University of Michigan, Michigan, US
3 Department of Pediatrics, Rajah Muthaiah Medical College, Annamalai University, IN

Abstract

Interest has grown in the role of oxygen derived free radicals such as superoxide anion and hydroxyl radicals as mediator of tissue damage in many disease processes. Lipid peroxidation (LPO) a free radical induced phenomenon was reported to be involved in the pathogenesis of glomerular disease such as nephrotic syndrome and acute poststreptococcal glomerulonephritis (APSGN) in children. APSGN is an inflammatory glomerular disease caused by the (5-hemolytic streptococcal infection of throat and skin. Epidemics of APSGN have been reported in different parts of the world. In APSGN children, blood loses its antioxidant defence and the children might suffer from prolonged oxidative stress with increased susceptibility to LPO and osmotic lysis. Therefore, it is expected that if APSGN children are supplemented with antioxidants along with the conventional antibiotic, it could prove beneficial in the quick amelioration of the disease.

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T. Devasena ¹, S. Lalitha ², K. Padma ³

Affiliations
1 Department of Biochemistry, Annamalai University, Annamalai Nagar, Tamilnadu, IN
2 Department of Obstetric and Gynaecology, University of Michigan, Michigan, US
3 Department of Pediatrics, Rajah Muthiah Medical College and Hospital, Annamalai University, Annamalai Nagar, Tamil Nadu, IN

Abstract

Minimal change nephrotic syndrome (MCNS) is the most common form of glomerular disease in children characterised by massive proteinuria. Corticosteroid therapy is currently recommended by German APN group (Arbeitsgemeinschaft Fur Paediatrische Nephrologie group -1990) for MCNS children. Prednisolone is commonly used for the treatment of MCNS children. However side effects of steroids (cataract, growth retardation, psychological disorders) adds to the morbidity and mortality of nephrotic syndrome patients.

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M. P. Vaidehi ¹, K. Padma ¹

Affiliations
1 University of Agricultural Sciences, Department of Rural Home Science, Hebbal Campus, Bangalore - 560 024, IN

Abstract

Soymilk has a high nutritive value with its protein and fat content comparable to cow's milk. Soya milk or its, curds can be regarded as a possible substitution or extender for dairy milk products in areas where milk productions scarce and prices consequently too high. Processing methods affect the nutritional quality of many food products. Fermentation in curds brought about in soya blended cow's milk and in instant cooking methods like extrusion cooking of soya in textured vegetable product (TVPJ) might have different influence on the protein quality.

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