Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Fermentation and its Role in Health and Disease : A Clinical Insight from the Lens of Therapeutic Intervention Strategy


Affiliations
1 Department of Biochemistry, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India
2 1Department of Biochemistry, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India
3 Department of Medical Lab Technology, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India
     

   Subscribe/Renew Journal


The importance of fermented food having medicinal value is well known, since ancient times and thus, is widely consumed worldwide. Since its discovery about centuries ago, there has been a lot of debate and research about the health benefits of fermented foods. As fermentation process enhances antioxidant activity of dietary food products such as fruits, milks, cereals, meat and fish by increasing the nutrients and vitamins. It offers health advantage, participates in various physiological activities and protects the cell against the toxic effects of free radicals which reflects its role in suppression of oxidative stress mediated disorders such as aging, hypertension, diabetes, cardiovascular disease and cancer etc. Various researches are going on to explore the hidden facts about the role of fermentation in health and diseases. However, the exact mechanism behind the involvement of fermented food contents in such events is not yet fully elucidated and needs further investigation. It’s protective properties and safety profile makes it an attractive therapeutic tool. In contrast, fermentation rarely produces some toxic contaminants and metabolites of the microbes into the food base. Therefore, the present article is focused on the current aspects related to health benefits of components of fermented food intake with special reference to oxidative stress mediated diseases and to understand its importance role in maintaining health diets as well.

Keywords

Antioxidants, Anti-Inflammatory, Anti-Obesity, Cardiovascular Disease, Diabetes.
User
Subscription Login to verify subscription
Notifications
Font Size

  • J. B. Prajapati, and B. M. Nair, “The history of fermented foods,” In E. R. Farnworth, Ed., Handbook of Fermented Functional Foods, 2nd ed. CRC Press, 2017, pp. 1-22.
  • J. Gal, “The discovery of biological enantioselectivity: Louis Pasteur and the fermentation of tartaric acid, 1857 - A review and analysis 150 yr later,” Chirality, vol. 20, no. 1, pp. 5-19, 2008.
  • https://www.vocabulary.com/dictionary/fermentation
  • F. Melini, V. Melini, F. Luziatelli, A. G. Ficca, and M. Ruzzi, “Health-promoting components in fermented foods: An up-to-date systematic review,” Nutrients, vol. 11, no. 5, p. 1189, 2019.
  • M. L. Marco, D. Heeney, S. Binda, C. J. Cifelli, P. D. Cotter, B. Foligné, M. Gänzle, R. Kort, G. Pasin, A. Pihlanto, E. J. Smid, and R. Hutkins, “Health benefits of fermented foods: Microbiota and beyond,” Curr. Opin. Biotechnol., vol. 44, pp. 94-102, 2017.
  • R. H. Liu, “Health-promoting components of fruits and vegetables in the diet,” Adv. Nutr., vol. 4, no. 3, pp. 384S-392S, 2013.
  • A. Bah, R. Ferjani, I. Fhoula, Y. Gharbi, A. Najjari, A. Boudabous, and H. I. Ouzari, “Microbial community dynsmic in tomato fruit during spontaneous fermentation and biotechnological characterization of indigenous lactic acid bacteria,” Ann. Microbiol., vol. 69, pp. 41-49, 2019.
  • H. K. Sharma, and P. S. Panesar, Technologies in Food Processing, 1st ed. Apple Academic Press, Palm Bay, FL, USA: 2018.
  • A. Blandino, M. E. Al-Aseeri, S. S. Pandiella, D. Cantero, and C. Webb, “Cereal-based fermented foods and beverages,” Food Res. Int., vol. 36, pp. 527-543, 2003.
  • L. Xing, R. Liu, S. Cao, W. Zhang, and Z. Guanghong, “Meat protein based bioactive peptides and their potential functional activity: A review,” Int J Food Sci Technol., vol. 54, no. 6, pp. 1956-1966, 2019.

Abstract Views: 113

PDF Views: 0




  • Fermentation and its Role in Health and Disease : A Clinical Insight from the Lens of Therapeutic Intervention Strategy

Abstract Views: 113  |  PDF Views: 0

Authors

Rahul Saxena
Department of Biochemistry, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India
Suyash Saxena
1Department of Biochemistry, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India
Ajit Pal Singh
Department of Medical Lab Technology, SAHS, Sharda University, Greater Noida, Uttar Pradesh, India

Abstract


The importance of fermented food having medicinal value is well known, since ancient times and thus, is widely consumed worldwide. Since its discovery about centuries ago, there has been a lot of debate and research about the health benefits of fermented foods. As fermentation process enhances antioxidant activity of dietary food products such as fruits, milks, cereals, meat and fish by increasing the nutrients and vitamins. It offers health advantage, participates in various physiological activities and protects the cell against the toxic effects of free radicals which reflects its role in suppression of oxidative stress mediated disorders such as aging, hypertension, diabetes, cardiovascular disease and cancer etc. Various researches are going on to explore the hidden facts about the role of fermentation in health and diseases. However, the exact mechanism behind the involvement of fermented food contents in such events is not yet fully elucidated and needs further investigation. It’s protective properties and safety profile makes it an attractive therapeutic tool. In contrast, fermentation rarely produces some toxic contaminants and metabolites of the microbes into the food base. Therefore, the present article is focused on the current aspects related to health benefits of components of fermented food intake with special reference to oxidative stress mediated diseases and to understand its importance role in maintaining health diets as well.

Keywords


Antioxidants, Anti-Inflammatory, Anti-Obesity, Cardiovascular Disease, Diabetes.

References