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Mahajan, Suresh V.
- Histopathological Findings in Uterus and Cervix of Hysterectomy Specimens
Abstract Views :308 |
PDF Views:74
Authors
Affiliations
1 Department of Pathology, Ruby Hall Clinic, Pune, IN
2 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital, and Research Centre, Vasantdada Nagar, Adgaon, Nashik-22003, IN
3 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital, and Research Centre, Vasantdada Nagar, Adgaon, Nashik-422003, IN
1 Department of Pathology, Ruby Hall Clinic, Pune, IN
2 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital, and Research Centre, Vasantdada Nagar, Adgaon, Nashik-22003, IN
3 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital, and Research Centre, Vasantdada Nagar, Adgaon, Nashik-422003, IN
Source
MVP Journal of Medical Sciences, Vol 2, No 1 (2015), Pagination: 26-29Abstract
Background: For centuries, the female reproductive system has been affected by various abnormalities and diseases and hence has been the subject of interest and the basis for the gynaecological practice. The uterus being a vital reproductive and hormone-responsive organ, is subjected to a variety of physiological changes and benign and malignant disorders. Aims and Objectives: To study the indications of hysterectomy, to study gross and histopathological features of uterus and cervix in hysterectomy specimens and correlate with clinical findings. Material and Methods: This was a descriptive study of the gross and histopathological findings of uterus and cervix in 150 hysterectomy specimens received in the department. The hysterectomy specimens received were fixed in 10% formalin for 24 hours, were examined grossly and necessary sections were obtained. The tissue pieces were then processed in automated tissue processor, well labelled paraffin blocks were made. Approximately 2-3μ thickness sections were cut with the help of microtome and were stained routinely by Hematoxylin & Eosin stain and special stains like PAS or other were used wherever necessary. The histopathological findings of uterus and cervix were noted and these findings were then correlated with clinical diagnosis. Results: Overall clinicopathological correlation was noted in all 150 cases. In cases of uterine fibroid it was 69.7% and 100% in case of endometrial carcinoma and cervical dysplasia. Most common pathology found was uterine leiomyomas in 48 cases and next to it was adenomyosis in 30 cases. Conclusion: It can be concluded that clinico-pathological correlation in case of endometrial cancer and uterine fibroid is excellent, but in case of DUB and prolapse uterus it varies. This signifies the importance of clinico-pathological correlation in all cases of hysterectomy to improve the clinical outcome and post-operative management.Keywords
Hysterectomy, Histopathology of Uterus and Cervix, Leiomyoma.Full Text
- Cytological Profile of Thyroid Lesions and it's Correlation with Clinical and Ultrasonography Findings
Abstract Views :233 |
PDF Views:57
Authors
Affiliations
1 Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Vasantdada Nagar, Adgaon, Nashik – 422003, IN
2 Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Vasantdada Nagar, Adgaon, Nashik - 422003, IN
3 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Adgaon, Nashik - 422203, Maharashtra, IN
1 Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Vasantdada Nagar, Adgaon, Nashik – 422003, IN
2 Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Vasantdada Nagar, Adgaon, Nashik - 422003, IN
3 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Adgaon, Nashik - 422203, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 3, No 1 (2016), Pagination: 28–32Abstract
Background: Thyroid gland is the first endocrine gland to develop, largest of all endocrine glands. Superficial location of thyroid gland allows evaluation of thyroid lesions by FNAC (fine needle aspiration cytology). Aims and Objective: To study cytological profile of thyroid lesions and correlate the results with Ultrasonography findings and clinical features. Material and Methods: This prospective study was carried out on 138 patients who came to the department from period of May 2012 to December 2014. Out of these 138 patients USG was carried out in 115 patients. FNAC of patients was performed and results of FNAC were correlated with those of USG reports and clinical features of the patient. Results: Out of 138 cases 83 (60.1%) cases were benign, 18(13.0%) cases were inflammatory, 2 (1.4%) cases were malignant, 28 (20.3%) were categorised as indeterminate, and 7 (5.1%) cases were inadequate. All the 2 malignant cases were given as neoplastic on USG. Conclusion: FNAC is the main diagnostic modality of choice for thyroid lesions, along with Ultrasonography and clinical examination it helps to come to the proper diagnosis.Keywords
FNAC, USG.Full Text
References
- Fehrenbach MJ, Herring SW. Illustrated Anatomy of the Head and Neck. 4th ed. China: Elsevier; 2012. Chapter 7 Glandular tissue; p.152–65.
- G-Kocjan. Fine Needle Aspiration Cytology- Diagnostic principals and dilemmas. 1st edition, Springer; 2006. Chapter 10, Principles of Safe practice: the role of FNAC in clinical management; 213–23.
- Sengupta A, Pal R, Kar S, Zaman FA, Sengupta S, PaL S. Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement. Journal of Natural Science, Biology and Medicine. 2011 Jan; 2(1):113–18.
- Bagga PK, Mahajan NC. Fine needle aspiration cytology of thyroid swellings: How useful and accurate is it? Indian Journal of Cancer; 2010 Oct–Dec; 47(4):437–42.
- Parikh UR, Goswami HM, Shah AM, Mehta NP, Gonsai RN. Fine Needle Aspiration Cytology (FNAC) Study of Thyroid Lesion. GMJ. 2012 Aug; 67(2):25–30.
- Likhar KS, Hazari RA, Gupta SG, Shukla U. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions: A hospital-based study. Thyroid Research and Practice; 2013 May-Aug; 10(2):68–71.
- Orell RS, Jayram Gita . Thyroid. In: Orell RS, Sterrett FG, editors. Fine Needle Aspiration Cytology. 5th ed. Elsevier Missouri: Churchill Livingstone; 2012. p. 119–55.
- Dhanadia A, Shah H, Dave A. Ultrasonographic and FNAC correlation of thyroid lesions. GMJ. 2014 Mar; 69(1):75–81.
- Afroze N, Kayani N, Hasan SH. Role of fine needle aspiration cytology in the diagnosis of palpable thyroid lesions. Indian J Pathol Microbiol. 2002 Jul; 45(3):241–46.
- Gupta M, Gupta S, Gupta VB. Correlation of Fine Needle Aspiration Cytology withHistopathology in the Diagnosis of Solitary Thyroid Nodule. Journal of Thyroid Research. 2010; 1–5.
- Sinna EA, Ezzat N. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions. Journal of the Egyptian National Cancer Institute. 2012; 24:63–70.
- Handa U, Garg S, Mohan H, Nagarkar N. Role of fine needle aspiration cytology in diagnosis and management of thyroid lesions: A study on 434 patients. Journal of Cytology. 2008 Jan; 25(1):13–7.
- Kantasueb S, Sukpan K, Mahanupab P. The study of thyroid lesions and the correlation between histopathological and cytological findings at Maharaj Nakorn Chiang Mai Hospital Between 2003 and 2007. Chiang Mai Med J. 2010; 49(3):105–10.
- Paarthipan N, Teli CG, Kate N, Jaiganesh S, Venkateswaran. A, Srinivas M. Role of high frequency ultrasound in evaluation of solitary thyroid nodule and comparison with fine needle aspiration cytology. Int Bio Med Res. 2012; 3(3):2158–62.
- Kaur K, Sonkhya N, Bapna AS, Mital P. A Comparative study of fine needle aspiration cytology, ultrsonography and radionuclide scan in the management of solitary thyroid nodule: A Prospective analysis of fifty cases. Indian Journal of Otolaryngology and Head and Neck Surgery. 2002 Apr-Jun; 54(2):96–01.
- AL-Obaidi SM, Abbas Zwain KM, Zaini HH. Comparative Study of Fine Needle Aspiration Cytology and Ultrasonography in the Management of Solitary Thyroid Nodule. The Iraqi Post Graduate Medical Journal. 2014; 5:68–73.
- Sehovic S, Begic A, Juric N, Celam M. Comparison between Ultrasound, Scintigraphy and Cytological Puncture in Diagnostics of Thyroid Gland Nodules. Med Arh. 2013 Jun; 67(3):198–01.
- Fine Needle Aspiration Cytological Study of Various Thyroid Lesions and its Clinical Correlation in a Tertiary Health Care Centre - A Prospective Study
Abstract Views :180 |
PDF Views:49
Authors
Affiliations
1 Department of Pathology, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
1 Department of Pathology, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 4, No 2 (2017), Pagination: 152-155Abstract
Background: Thyroid gland is the largest endocrine gland in the body and the first to develop in fetal life. Its superficial location allows evaluation of thyroid lesions by FNAC (fine needle aspiration cytology). Aims and Objective: To study cytological profile of thyroid lesions and correlate the results with clinical features. Material and Methods: This prospective study was carried out on 112 patients who came to the department from period of August 2014 to December 2016. FNAC of patients was performed and results of FNAC were correlated with clinical features of the patient. Results: Out of 112 cases studied, 78(69.6%) cases were diagnosed as Benign, 13 (11.6%) cases were diagnosed as Inflammatory, 19 (16.9%) cases were diagnosed as Follicular lesions and 2 (1.7%) cases were diagnosed as malignant. Conclusion: FNAC is one of the useful primary diagnostic tool for thyroid lesions.Keywords
Thyroid Lesions, FNAC.Full Text
References
- Vander JB, Gaston EA, Dawber TR. The significance of nontoxic thyroid nodule: Final report of a 15 year study of incidence of thyroid malignancy. Ann Int Med. 1968; 69:537.https://doi.org/10.7326/0003-4819-69-3-537 PMid:5673172
- Sengupta A, Pal R, Kar S, Zaman FA, Sengupta S, PaL S. Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement. Journal of Natural science, Biology and Medicine. 2011 Jan; 2(1):113–8. https://doi.org/10.4103/0976-9668.82308 PMid:22470244 PMCid:PMC3312690
- Davidson HG, Gonzalez-Campora R. Thyroid (Fine needle aspiration of various organs and Body sites). In Bibbo M, editor. Comphresive cytopathology. 3rd ed. Saunders company; 2008. p. 633–70.
- Bamanikar S, Soraisham P, Jadhav S, Kumar H, Jadhav P, Bamanikar A. Cytohistology and clinical correlation of Thyroid gland lesions. Journal of Clinical Cancer Investigation. 2014 May-Jun; 3(3):208–12. https://doi.org/10.4103/22780513.132112
- Orell RS, Gita J. Thyroid. In: Orell RS, Sterrett FG, editors. Fine needle aspiration cytology. 5th ed. Elsevier Missouri: Churchill Livingstone; 2012. p. 119–55.
- Chetan VR, Veeresalingam B, Kumar KM, Teja P, et al. A study on the clinical manifestations and the incidence of benign and malignant tumors in a solitary thyroid nodule. Int J Res Med Sci. 2013 Nov; 1(4):429–34. https://doi.org/10.5455/2320-6012.ijrms20131123
- Dhanadia A, Shah H, Dave A. Ultrasonographic and FNAC correlation of thyroid lesions. Gujarat Medical Journal. 2014 Mar; 69(1):75–81.
- Chandanwale S, Singh N, et al. Clinicopatholological correlation of thyroid nodules. Int J Pharm Biomed Sci. 2012; 3(3):97–102.
- Handa U, Garg S, Mohan H, Nagarkar N. Role of fine needle aspiration cytology in diagnosis and Role of fine needle aspiration cytology in diagnosis and management of thyroid lesions: A study on 434 patients. Journal of cytology. 2008 Jan; 25(1):13–7. https://doi.org/10.4103/0970-9371.40652
- Likhar KS, Hazari RA. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions: A hospital-based study. Thyroid Research and Practice. 2013 May-Aug; 10(2):68–71.
- Bagga PK, Mahajan NC. Fine needle aspiration cytology of thyroid swellings: How useful and accurate is it? Indian Journal of cancer. 2010 oct-dec; 47(4):437–42. https://doi.org/10.4103/0019-509X.73564 PMid:21131759
- Afroze N, Kayani N, Hasan SH. role of fine needle aspiration cytology in the diagnosis of palpable thyroid lesions. Indian Journal of Pathology and Microbiology. 2002 Jul; 45(3):241–6. PMid:12785159
- Venkatachalapathy TS, Sreeramulu PN, Krishna MR. A prospective study of clinical, sonological and pathological evaluation of thyroid nodule. Thyroid Disorders and Therapy.2012; 1(2):109.
- Mathur DR, Sharma R. Diagnostic accuracy of Fine Needle Aspiration Cytology (FNAC) of the thyroid gland lesions. International Journal of Health Sciences and Research. 2012 Nov; 2(8):1–7.