Research Journal of Pharmaceutical Dosage Form and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

A Recent attempt made on Fast Disintegrating Tablets: A Precise Review


Affiliations
1 Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
     

   Subscribe/Renew Journal


The purpose of this study was to investigate previous research on fast-acting pills. Fast dissolving tablets (FDTs) have become a rapidly emerging field in the pharmaceutical business over the last ten years. For the administration of many medications, oral drug delivery remains the recommended method. Scientists have developed FDTs with increased patient compliance and convenience during insertion into the mouth because of recent technological advances. For simple administration of active pharmaceutical substances, these tablets crumble or dissolve in the mouth without the use of water. Because of the formulation's popularity and use, several FDT technologies have been developed. FDTs are solid unit dosage forms that dissolve or disintegrate quickly in the mouth without the use of water or chewing. FDT shines in areas where pediatrics and geriatricshave trouble swallowing traditional tablets and capsules. FDT is a new drug delivery system that is intended for rapid dissolution and action, as well as treating acute illnesses with greater patient compliance. The authors gathered enough data from previous FDT trials. This review article can be used by researchers to quickly obtain latest literature on FDT.

Keywords

Disintegrating, Literature, Mouth dissolving, Past work, Polymers.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Ahad HA, Ksheerasagare T, Chelluru A, Haranath C, Reddy GS, Krishna JV. Herbal Mucilage attempted as a Super disintegrating agent in Oral Disintegrating Tablets. Research Journal of Pharmacy and Technology. 2020 Nov 1;13(11):5489-92.

  • Jwalapuram R, Ahad HA, Haranath C, Thadipatri R, Varshitha CV, Kumar YB. A desktop reference to the solubility enhancement of drugs with the aid of surfactants. (2020). Int. J. Life Sci. Pharma Res.;11(5):11-16.

  • Ahad HA, Ksheerasagare T, Chelluru A, Haranath C, Reddy GS, Krishna JV. Herbal Mucilage attempted as a Super disintegrating agent in Oral Disintegrating Tablets. Research Journal of Pharmacy and Technology. 2020 Nov 1;13(11):5489-92.

  • Chinthaginjala H, Ahad HA, Samhitharao B, Yasaswini VS, Madana G, Varam NJ, Dasari R. Formulation and In Vitro Evaluation of Fast Disintegrating Tablets of an Anti-Inflammatory Drug using Natural Super Disintegrating Agents. (2). Int. J. Life Sci. Pharma Res. 2021: 9-18.

  • Annepogu H, Hindustan Abdul AH, Nayakanti D. Determining the best poloxamer carrier for thiocolchicoside solid dispersions. Turkish Journal of Pharmaceutical Sciences. 2020 Aug;17(4):372.

  • Ahad HA, Chinthaginjala H, Rahamtulla S, Pallavi BP, Shashanka C, Prathyusha J. A Comprehensive report on Solid Dispersions by Factorial Design. Asian Journal of Research in Chemistry. 2021 Aug 3;14(4):297-301.

  • Gnanaprakash K, Mallikarjuna Rao K, Chandra Sekhar KB, Chetty K, Alagusundaram M, Ramkanth S. Formulation, and evaluation of fast dissolving tablets of valdecoxib. Int J PharmTech Res. 2009; 1:1387-93.

  • Bhardwaj S, Jain V, Jat RC, Mangal A, Jain S. Formulation, and evaluation of fast dissolving tablet of aceclofenac. International journal of drug delivery. 2010 Jan 1;2(1), 93-97.

  • Prabhu P, Malli R, Koland M, Vijaynarayana K, D’Souza U, Harish NM, Shastry CS, Charyulu RN. Formulation and evaluation of fast dissolving films of levocitirizine di hydrochloride. International journal of pharmaceutical investigation. 2011 Apr;1(2):99.

  • kumar Gudas G, Manasa B, Rajesham VV, Kumar SK, Kumari JP. Formulation and evaluation of fast dissolving tablets of Chlorpromazine HCl. Journal of Pharmaceutical sciences and Technology201. 2010;2(1):99-102.

  • Basu B, Bagadiya A, Makwana S, Vipul V, Batt D, Dharamsi A. Formulation, and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. Journal of advanced pharmaceutical technology & research. 2011 Oct;2(4):266.

  • Kavitha K, Sandeep DS, Yadawad M, Mangesh M. Formulation, and evaluation of oral fast dissolving tablets of promethazine HCL by sublimation method. International Journal of PharmTech Research. 2011;3(2):659-63.

  • Siraj S, Nazim S, Pravin G, Afsar S, Majaz Q. Formulation, and evaluation of aceclofenac fast dissolving tablets. Int Res J Pharmacy. 2011 Jan;2(1):100-5.

  • Patil MG, Kakade SM, Pathade SG. Formulation and evaluation of orally disintegrating tablet containing tramadol hydrochloride by mass extrusion technique. Journal of Applied Pharmaceutical Science. 2011 Aug 1;1(6):178.

  • Kumar KS, Boddeda B, Ratna JV. Formulation And Evaluation of Fast Dissolving Tablets of Felodipine. International Journal of Engineering Research & Technology. 2012 Nov;1(9). 1-16.

  • Remya PN, Damodharan N, Sharma L. Formulation, and evaluation of fast disintegrating orodispersible tablets of ondansetron hydrochloride. Journal of Pharmaceutical Sciences and Research. 2012 May 1;4(5):1810.

  • Sathali AA, Prakash T. Formulation and evaluation of fast dissolving tablets of lamivudine. IJPBR. 2012; 3:98-112.

  • Sukhavasi S, Kishore VS. Formulation and evaluation of fast dissolving tablets of amlodipine besylate by using Fenugreek seed mucilage and Ocimum basilicum gum. International current pharmaceutical journal. 2012 Aug 4;1(9):243-9.

  • Dhiman V, Jain G, Jagtap V, Sheorey RV. Formulation and in-vitro evaluation of fast dissolving tablets of telmisartan. Int J Pharm Life Sci. 2012 Nov; 3:2159-64.

  • Rane DR, Gulve HN, Patil VV, Thakare VM, Patil VR. Formulation and evaluation of fast dissolving tablet of albendazole. International Current Pharmaceutical Journal. 2012 Sep 5;1(10):311-6.

  • Bansal S, Bansal M, Garg G. Formulation, and evaluation of fast dissolving film of an antihypertensive drug. International Journal of Pharmaceutical, Chemical & Biological Sciences. 2013 Oct 1;3(4). 1-12.

  • Satpute MM, Tour NS. Formulation and in vitro evaluation of fast dissolving tablets of metoprolol tartrate. Brazilian Journal of pharmaceutical sciences. 2013; 49:783-92.

  • Chauhan K, Parashar B, Chandel A, Thakur V. Formulation, and evaluation of fast dissolving tablets of telmisartan. International Journal of Pharmaceutical Sciences and Research. 2013 Apr 1;4(4):1514

  • Saroha KA, Kumar GA, Paul YA. Formulation and evaluation of fast dissolving tablets of amoxicillin trihydrate using synthetic superdisintegrants. Int J Pharm Bio Sci. 2013;4(1):254-62.

  • Damodar R, Movva B, Mallikarjun PN, Pasumarthy C, Kona N, Varsha PV. Formulation and evaluation of fast dissolving tablets of diclofenac sodium by novel whole technology. J Mol Pharm Org Process Res. 2014 Jul 31;2(116):2.

  • Pingale AP, Katti SA, Choudhari RK, Bhambar RS. Formulation and evaluation of fast disintegrating tablet of eletriptan hydrobromide. Res J Pharm Technol. 2014 Jul 29; 7:792-7.

  • Kola M, Mallik S, Palle P, Kamarapu P. Fast disintegrating tablets of Nevirapine. Asian Journal of Pharmaceutical Research. 2014 Sep 1;4(3). 1-8.

  • Saini S, Mohan B, Gill N. Formulation and Evaluation of Fast Dissolving Tablet of Silymarin. PharmaTutor. 2014 Sep 1;2(9):81- 90.

  • Sarfraz RM, Khan HU, Mahmood A, Ahmad M, Maheen S, Sher M. Formulation, and evaluation of mouth disintegrating tablets of atenolol and atorvastatin. Indian journal of pharmaceutical sciences. 2015 Jan;77(1):83.

  • Haque SE, Sheela A. Development of polymer-bound fastdissolving metformin buccal film with disintegrants. International journal of nanomedicine. 2015;10(Suppl 1):199.

  • Soni A, Raju L. Formulation and evaluation of fast disintegrating tablet containing hydrochlorothizide. Indian Journal of Pharmacy and Pharmacology, 2015; 2 (2): 119. 2015 Apr;133.

  • Ibrahim MA, Amal El Sayeh F. Optimized furosemide taste masked orally disintegrating tablets. Saudi Pharmaceutical Journal. 2017 Nov 1;25(7):1055-62.

  • Dave V, Yadav RB, Ahuja R, Yadav S. Formulation design and optimization of novel fast dissolving tablet of chlorpheniramine maleate by using lyophilization techniques. Bulletin of Faculty of Pharmacy, Cairo University. 2017 Jun 1;55(1):31-9.

  • Kharde A, Sagar N. Formulation and Evaluation of Fast Disintegrating Tablet of Carvedilol, 2018; 13 (1): 196-212.

  • Saif AA, Alburyhi MM, Noman MA. Formulation and Evaluation of Ketoprofen Fast Dissolving Tablets. International Journal of Sciences. 2018;7(09):27-39.

  • Muralidhar S, Narayana TV, Kumar CS, Arun MA. Formulation And Evaluation of Fast Dissolving Tablets by Addition Of Different Concentra-tions Of Superdisintegrant And By Effervescent Technology. International Journal of Pharmaceutics and Drug Analysis. 2019 Jan 30:1-0.

  • Mane S, Bathe R, Awatade S. Formulation and Evaluation of Fast Disintegrating Tablets of Atenolol Using Natural and Synthetic Superdisintegrants. Journal of Drug Delivery and Therapeutics. 2019 Apr 15;9(2-s):150-8.

  • Aruna M, Rasheed SH. Formulation, and evaluation of fast disintegrating tablets of metoprolol succinate using various superdisintegrants. International Journal of Research in Pharmaceutical Sciences and Technology. 2019 Oct 12;1(2):79-83.

  • Kumar K, Chopra H, Sharma GK. Formulation, and evaluation of fast dissolving tablet of montelukast by using co-processed excipients. Research Journal of Pharmacy and Technology. 2019;12(11):5543-8.

  • Nurhabibah N, Sriarumtias FF, Fauziah S, Auliasari N, Hindun S. Formulation, and evaluation fast disintegrating film salbutamol sulfat using HPMC E15. InJournal of Physics: Conference Series 2019; 1402 (5); 55093.

  • Kaur M, Mittal A, Gulati M, Sharma D, Kumar R. Formulation, and in vitro Evaluation of Fast Dissolving Tablets of Febuxostat Using Co-Processed Excipients. Recent patents on drug delivery & formulation. 2020 Mar 1;14(1):48-62.

  • Malang M, Jain N, Koshta A, Malviya S, Kharia A. Formulation, and evaluation of fast dissolving tablet of paracetamol and chlorpheniramine maleate. IJPSR. 2020;11(3):1232-42.

  • Shrilatha KS, Senthilkumar K, Likhith HM, Gupta BP. Formulation and In-Vitro Evaluation of Fast Dissolving Tablets of Anti-Ulcer Drugs 2020; 8 (2): 49-59

  • Malang M, Jain N, Koshta A, Malviya S, Kharia A. Formulation, and evaluation of fast dissolving tablet of paracetamol and chlorpheniramine maleate. IJPSR. 2020;11(3):1232-42.

  • Eraga SO, Okolo CM, Odionyenma BU, Mbadugha CE, Iwuagwu MA. A Comparative Evaluation of Fast Dissolving Tablets of Acetaminophen Using Super-disintegrant Blends and Sublimation Method. Journal of Phytomedicine and Therapeutics. 2020 Jul 24;19(1):375-86.

  • Gowthamy PG, Snehal YK. Formulation, Development and Evaluation of Fast Disinte-grating Piroxicam Tablets. Int J Pharma Sci. 2020;1(1):1-2.

  • Teaima MH, Abdel-Haleem KM, Osama R, El-Nabarawi MA, Elnahas OS. A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using CoProcessed Excipients: Formulation, Characterization and Pharmacokinetic Study. Drug Design, Development and Therapy. 2021; 15:4229.

  • Mushtaq M, Fazal N, Niaz A. Formulation, and evaluation of fastdisintegrating tablets of flurbiprofen and metoclopramide. Journal of Pharmaceutical Innovation. 2021 Sep;16(3):419-38.

  • Singh I, Zandu SK, Kumari R. Formulation and evaluation of fast disintegrating tablets of domperidone using chitosan-glycine conjugates as superdisintegrant. Thai Journal of Pharmaceutical Sciences (TJPS). 2021 Jan 13;45(1): 32-40.

  • Ingale AS, Ahire SS, Ahire SI, Patil PR. Formulation, and evaluation of fast dissolving tablets of captopril 2021; 17(02): 123–130

  • Choursiya A, Pandit D. Formulation and Evaluation of fast dissolving tablets of Lansoprazole by Solubility Enhancement Technique. Current Research in Pharmaceutical Sciences. 2021 Sep 14:54-64.

  • Bhargava VH, Sable PS, Kulkarni DA, Darekar GP. Formulation and evaluation of mouth dissolving tablet of benazepril hydrochloride. Research Journal of Pharmacy and Technology. 2021 Jun 1;14(6):3161-6.

  • Bindal R, Indurkhya A. Formulation and Evaluation of Ketorolac Tromethamine Mouth Dissolving Tablets. Journal of Drug Delivery and Therapeutics. 2021 Jan 15;11(1):60-4.

  • Rao SV, Sravya K, Padmalatha K. Formulation and Evaluation of Fast Dissolving Tablets of Atorvastatin Using Novel Co-Processed Excipients. Journal of Pharmaceutical Sciences and Research. 2021 Aug 1;13(8):474-80.

  • Thorat KV, Khade P, Kakade S, Bhosale A. Formulation, and evaluation of fast dissolving mouth film of domperdone. Methods. 2021; 10 (12); 2104-2121.

  • Khadka M, Khanal DP, Baniya DP, Karki P, Shrestha S. Formulation, and evaluation of oral disintegrating tablets of furosemide. World Journal of Current Medical and Pharmaceutical Research. 2021; 3(6): 149-156.


Abstract Views: 175

PDF Views: 0




  • A Recent attempt made on Fast Disintegrating Tablets: A Precise Review

Abstract Views: 175  |  PDF Views: 0

Authors

Hindustan Abdul Ahad
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
Haranath Chinthaginjala
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
Nagarajugari Kavyasree
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
Jyothi Vinay Krishna
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
Sushma Papireddypalli
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India
Kotlo Saijyoshna
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, K.R. Palli Cross, Chiyyedu (P), Ananthapuramu - 515721, AP,, India

Abstract


The purpose of this study was to investigate previous research on fast-acting pills. Fast dissolving tablets (FDTs) have become a rapidly emerging field in the pharmaceutical business over the last ten years. For the administration of many medications, oral drug delivery remains the recommended method. Scientists have developed FDTs with increased patient compliance and convenience during insertion into the mouth because of recent technological advances. For simple administration of active pharmaceutical substances, these tablets crumble or dissolve in the mouth without the use of water. Because of the formulation's popularity and use, several FDT technologies have been developed. FDTs are solid unit dosage forms that dissolve or disintegrate quickly in the mouth without the use of water or chewing. FDT shines in areas where pediatrics and geriatricshave trouble swallowing traditional tablets and capsules. FDT is a new drug delivery system that is intended for rapid dissolution and action, as well as treating acute illnesses with greater patient compliance. The authors gathered enough data from previous FDT trials. This review article can be used by researchers to quickly obtain latest literature on FDT.

Keywords


Disintegrating, Literature, Mouth dissolving, Past work, Polymers.

References