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Pandit, Vinay
- A Detailed Review on Fast Dissolving Niosomal Films for Sublingual Drug Delivery
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Authors
Affiliations
1 Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, Jawalamukhi, Kangra (H.P.) 177101,, IN
1 Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, Jawalamukhi, Kangra (H.P.) 177101,, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 14, No 2 (2022), Pagination: 163-170Abstract
Fast dissolving or Quick-dissolving dosage forms have great importance in the pharmaceutical field due to their special properties and advantages. Fast-dissolving dosage forms breakdown immediately in the salivary fluids of the oral cavity within a minute, where they release the active pharmaceutical ingredient. Sublingual drug delivery system is a novel route of drug administration in which the drug substance is placed under the tongue and is directly absorbed via the blood vessels and produces the immediate onset of action. Noisome are closed bilayer vesicles formed by self-assembly of nonionic surfactant in an aqueous medium. Noisome is similar to liposome but has the ability to increase the stability of the drug. Formulated niosomes are added into the film forming polymers to obtain sublingual niosomal films. Fast dissolving niosomal film is suitable for the drugs which show high first-pass metabolism or hepatic metabolism, low bioavailability drugs, and have a short half life drugs. Fast Dissolving Niosomal Films used to improve the oral bioavailability and reduce the dose and dosing frequency, which reduce systemic side effects and as well as cost-effective. Niosomes allow the prolonged release of the drug and film was used to increase the bioavailability of drugs via the sublingual route of drug administration. Fast dissolving niosomal films have great importance during emergency conditions like allergy, short-term spasm, and asthma whenever an immediate onset of action is required. Fast dissolving films are also suitable for pediatric, geriatric, and dysphasic patients or patients with fear of choking.Keywords
Fast-dissolving drug–delivery, Geriatric, Solvent casting, Pediatric, Bioavailability.
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- Application of Berberine on Skin Diseases: A Review
Abstract Views :345 |
PDF Views:0
Authors
Keshav Dhiman
1,
Anshul Sharma
1,
Anshul Sharma
1,
Kamya Goyal
2,
Vinay Pandit
1,
M. S. Ashawat
1,
Shammy Jindal
1
Affiliations
1 Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog Jawalaji Dist - Kangra (H.P.), IN
2 Department of Pharmaceutical Analysis and Quality Assurance, Laureate Institute of Pharmacy, Kathog Jawalaji Dist - Kangra (H.P.), IN
1 Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog Jawalaji Dist - Kangra (H.P.), IN
2 Department of Pharmaceutical Analysis and Quality Assurance, Laureate Institute of Pharmacy, Kathog Jawalaji Dist - Kangra (H.P.), IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 14, No 4 (2022), Pagination: 304-308Abstract
The plants containing berberine have been used for the treatment of skin diseases, inflammatory disorders, and reducing fevers, wound healing, digestive and respiratory diseases and in treatment of tumors. By taking the specific properties of the berberine, this review describes the method mentioned in the literature regarding the berberine extraction. Furthermore, many experimental and clinical studies suggest that berberine has several pharmacological activities such as antioxidative, cardioprotective, nephroprotective, and hepatoprotective effect. This review summarizes the information about botanical occurrence, traditional uses and pharmacological effects of berberine and berberine containing plants.Keywords
Berberine, Skin Diseases, Psoriasis.References
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