Antipyretic activity of Ethanolic Extract of Premna corymbosa Rottl. Leaves (Verbenacea)

Preliminary phytochemical screening of leaves of Premna corymbosa Rottl demonstrated the presence of alkaloid, glycosides, flavanoids, steroids and triterpenoids. Antipyretic cativity of ethanolic extract of Premna corymbosa rottl. Leaves was tested by Brewer's yeast induced pyrexia method.decrease I temperature produced by ethanolic extract in a dose of 100, 200 mg/kg in male rat was measured and compared with reference standard paracetamol(25 mg/kg).