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Preliminary Screening of Syzygium cumini and Achyranthes aspera for Their Anthelmintic Activity


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1 K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
     

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The aim of present study is to determine the anthelmintic activity of crude extracts from leaves of Syzygium cumini and Achyranthes aspera. Anthelmintic activity of crude extracts were investigated against earthworms (Pheretima posthuma) using Albendazole as reference standard. Syzygium cumini leaves were extracted with different solvents like n-Hexane, Benzene, Chloroform and Methanol. Achyranthes aspera were extracted with Alcohol and Water solvents. The results of anthelmintic activity reveals that the methanol, chloroform, n-hexane extracts of Syzygium cumini leaves exhibits better anthelmintic activity, when compared to standard Albendazole .Where as benzene extract of Syzygium cumini leaves exhibit comparatively less anthelmintic activity. Alcohol and water extracts of Achyranthes aspera leaves also exhibit comparative anthelmintic activity to that of standard Albendazole. The present study proves the usefulness of the plants, Syzygium cumini and Achyranthes aspera as potential anthelmintic agents.

Keywords

Syzygium cumini, Achyranthes aspera, Anthelmintic Activity, Pheretima posthuma (Indian Adult Earth Worm).
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  • Preliminary Screening of Syzygium cumini and Achyranthes aspera for Their Anthelmintic Activity

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Authors

K. Sujitha
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
A. Phani Sri
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
P. M. Mohan Rao
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
Lal Mahammed
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
K. Srinivasarao
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India
V. Karuna Sree
K. V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520010(A.P), India

Abstract


The aim of present study is to determine the anthelmintic activity of crude extracts from leaves of Syzygium cumini and Achyranthes aspera. Anthelmintic activity of crude extracts were investigated against earthworms (Pheretima posthuma) using Albendazole as reference standard. Syzygium cumini leaves were extracted with different solvents like n-Hexane, Benzene, Chloroform and Methanol. Achyranthes aspera were extracted with Alcohol and Water solvents. The results of anthelmintic activity reveals that the methanol, chloroform, n-hexane extracts of Syzygium cumini leaves exhibits better anthelmintic activity, when compared to standard Albendazole .Where as benzene extract of Syzygium cumini leaves exhibit comparatively less anthelmintic activity. Alcohol and water extracts of Achyranthes aspera leaves also exhibit comparative anthelmintic activity to that of standard Albendazole. The present study proves the usefulness of the plants, Syzygium cumini and Achyranthes aspera as potential anthelmintic agents.

Keywords


Syzygium cumini, Achyranthes aspera, Anthelmintic Activity, Pheretima posthuma (Indian Adult Earth Worm).