Research Journal of Pharmacognosy and Phytochemistry

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Anti-Ulcer Effects of Ipomoea aquatica forsk Leaves Against Gastric Ulcers in Rats


Affiliations
1 P.G. Dept .of Biochemistry, Meenakshmi Chandrasekaran Arts and Science College, Pattukkottai 614 601, Thanjavur, India
2 Department of Siddha Medicine, Tamil University, Vakaiyur, Thanjavur - 613 010, Tamilnadu, India
     

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The anti ulcer effects of aqueous, chloroform and ethanol extracts prepared from the Ipomoea aquatica forsk leaves was evaluated in rats employing the pylorus ligation, stress induced and aspirin induced models. The parameters taken to assess anti ulcer activity were volume of gastric juice, free acidity, total acidity and ulcer index. The results indicated that chloroform extract significantly (p<0.001) decreased the volume of gastric acid secretions, free acidity and total acidity and ulcer index.

Keywords

Ipomoea aquatica forsk Antiulcer Effect, Pylorus ligation, Aspirin, Stress.
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  • Anti-Ulcer Effects of Ipomoea aquatica forsk Leaves Against Gastric Ulcers in Rats

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Authors

P. Muthukumaran
P.G. Dept .of Biochemistry, Meenakshmi Chandrasekaran Arts and Science College, Pattukkottai 614 601, Thanjavur, India
K. Pattabiraman
Department of Siddha Medicine, Tamil University, Vakaiyur, Thanjavur - 613 010, Tamilnadu, India

Abstract


The anti ulcer effects of aqueous, chloroform and ethanol extracts prepared from the Ipomoea aquatica forsk leaves was evaluated in rats employing the pylorus ligation, stress induced and aspirin induced models. The parameters taken to assess anti ulcer activity were volume of gastric juice, free acidity, total acidity and ulcer index. The results indicated that chloroform extract significantly (p<0.001) decreased the volume of gastric acid secretions, free acidity and total acidity and ulcer index.

Keywords


Ipomoea aquatica forsk Antiulcer Effect, Pylorus ligation, Aspirin, Stress.