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Anthelmintic Activity of Spondias pinnata (Linn. F) Kurz


Affiliations
1 Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot District, Gujarat -360 440, India
2 Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura-799005, India
     

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Present study reports anthelmintic activity of various extracts of the bark of Spondias Pinnata against Indian earthworms Pheritima posthuma. The results revealed that all the tested extracts of Spondias Pinnata bark possess anthelmintic activity in a dose dependant manner. Potency of the test samples was found to be inversely proportional to the time taken for paralysis/death of the worms. The activities were comparable with the reference drug piperazine citrate. Among the tested extracts, the chloroform extract was found to possess promising anthelmintic activity in comparison to other extracts. The present study therefore justifies its use in the folklore remedies as an anthelmintic drug of natural origin.

Keywords

Anthelmintic, Spondias Pinnata, Pheritima Posthuma, Piperazine Citrate.
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  • Anthelmintic Activity of Spondias pinnata (Linn. F) Kurz

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Authors

Sumanta Mondal
Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot District, Gujarat -360 440, India
Gouri Kishore Dash
Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot District, Gujarat -360 440, India
Rishi Raj Chhetree
Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura-799005, India

Abstract


Present study reports anthelmintic activity of various extracts of the bark of Spondias Pinnata against Indian earthworms Pheritima posthuma. The results revealed that all the tested extracts of Spondias Pinnata bark possess anthelmintic activity in a dose dependant manner. Potency of the test samples was found to be inversely proportional to the time taken for paralysis/death of the worms. The activities were comparable with the reference drug piperazine citrate. Among the tested extracts, the chloroform extract was found to possess promising anthelmintic activity in comparison to other extracts. The present study therefore justifies its use in the folklore remedies as an anthelmintic drug of natural origin.

Keywords


Anthelmintic, Spondias Pinnata, Pheritima Posthuma, Piperazine Citrate.