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Free Radical Scavenging Activity of Scindapsus officinalis Fruits


Affiliations
1 Dept. of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
2 Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
     

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In the present study, coarse powder of Scindapsus officinalis (Roxb.) Schott. fruit was extracted successively using hexane, chloroform, ethyl acetate and 50% ethanol. The ethyl acetate and 50% ethanolic extracts were investigated for its antioxidant activity by using nitric oxide and DPPH radical scavenging methods. The IC50 value was also calculated. Ascorbic acid was used as a standard. Both 50% ethanolic and ethyl acetate extract were found to exert concentration dependent free radical scavenging activity but former extract was more effective than the later on. The highest free radical scavenging activity by Scindapsus officinalis fruit extracts was observed at concentration of 1000 μg/ml.

Keywords

Scindapsus officinalis (Roxb.) Schott., Antioxidant, Free Radicals, IC50 Value.
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  • Free Radical Scavenging Activity of Scindapsus officinalis Fruits

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Authors

Malarkodi Velraj
Dept. of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
Mahendra Singh
Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
V. Ravichandiran
Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
S. Jayakumari
Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
A. Vijayalakshmi
Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India
Sanjay Ragela
Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, India

Abstract


In the present study, coarse powder of Scindapsus officinalis (Roxb.) Schott. fruit was extracted successively using hexane, chloroform, ethyl acetate and 50% ethanol. The ethyl acetate and 50% ethanolic extracts were investigated for its antioxidant activity by using nitric oxide and DPPH radical scavenging methods. The IC50 value was also calculated. Ascorbic acid was used as a standard. Both 50% ethanolic and ethyl acetate extract were found to exert concentration dependent free radical scavenging activity but former extract was more effective than the later on. The highest free radical scavenging activity by Scindapsus officinalis fruit extracts was observed at concentration of 1000 μg/ml.

Keywords


Scindapsus officinalis (Roxb.) Schott., Antioxidant, Free Radicals, IC50 Value.