Research Journal of Pharmacognosy and Phytochemistry

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Evaluation of in vitro Anti-Oxidant Activity of Premna integrifolia Linn. Mant. Root


Affiliations
1 “Shrikunj” 3-Archana Park, B/H Krishna Complex, University Road, Rajkot-360005, Gujarat, India
2 Dept. of Pharmacognosy, S.J. Thakkar Pharmacy College, Rajkot, India
3 Dept. of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad, India
4 Dept. of Pharmacology L. M. College of Pharmacy, Ahmedabad, India
     

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Root of Premna integrifolia known under common name Arni/Agnimantha which is an important constituent of well known formulation, Dashmularistha used for various ailments. In the present study methanolic extract of the ischolar_mains was evaluated for its in-vitro antioxidant activity using the anti radical, superoxide scavenging, anti lipid peroxidation, hydroxyl radical scavenging and nitric oxide scavenging, assays. The extract showed significant anti-oxidant activity in all the assays. The study scientifically demonstrated the use of P. integrifolia as a potential source of natural antioxidant.

Keywords

P. integrifolia, Verbanaceae, Anti-Oxidant Activity.
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  • Evaluation of in vitro Anti-Oxidant Activity of Premna integrifolia Linn. Mant. Root

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Authors

R. H. Gokani
“Shrikunj” 3-Archana Park, B/H Krishna Complex, University Road, Rajkot-360005, Gujarat, India
M. A. Rachchh
Dept. of Pharmacognosy, S.J. Thakkar Pharmacy College, Rajkot, India
S. K. Lahiri
Dept. of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad, India
D. D. Santani
Dept. of Pharmacology L. M. College of Pharmacy, Ahmedabad, India
M. B. Shah
Dept. of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad, India

Abstract


Root of Premna integrifolia known under common name Arni/Agnimantha which is an important constituent of well known formulation, Dashmularistha used for various ailments. In the present study methanolic extract of the ischolar_mains was evaluated for its in-vitro antioxidant activity using the anti radical, superoxide scavenging, anti lipid peroxidation, hydroxyl radical scavenging and nitric oxide scavenging, assays. The extract showed significant anti-oxidant activity in all the assays. The study scientifically demonstrated the use of P. integrifolia as a potential source of natural antioxidant.

Keywords


P. integrifolia, Verbanaceae, Anti-Oxidant Activity.