Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Cucurbitacin Glycosides from the Fruits of Citrullus colocynthis (L).


Affiliations
1 Department of Chemistry, Chettinad College of Engineering and Technology, Karur, 639114, India
2 ADM College for Women, Nagappattinam, 611 001, India
     

   Subscribe/Renew Journal


Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) is an Iranian medicinal plant that has traditionally been used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes. As part of our on-going studies on Iranian medicinal plants, thorough phytochemical investigation was carried out on this plant. Solvent extraction method was employed to isolate compounds from the ethyl acetate and ethyl methyl ketone fractions of the hydro-ethanolic (90%) extract of the fruits of the locally grown C. colocynthis. Structures of the isolated compounds were elucidated by spectroscopic means. Two cucurbitacin glucosides, 2-O-β-D-glucopyranosylcucurbitacin I and 2-O-β-D-glucopyranosylcucurbitacin L were isolated and identified.

Keywords

Citrullus colocynthis, Cucurbitaceae, Cucurbitacin I, Cucurbitacin L.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 233

PDF Views: 0




  • Cucurbitacin Glycosides from the Fruits of Citrullus colocynthis (L).

Abstract Views: 233  |  PDF Views: 0

Authors

N. Sampath Kumar
Department of Chemistry, Chettinad College of Engineering and Technology, Karur, 639114, India
G. Madhurambal
ADM College for Women, Nagappattinam, 611 001, India

Abstract


Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) is an Iranian medicinal plant that has traditionally been used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes. As part of our on-going studies on Iranian medicinal plants, thorough phytochemical investigation was carried out on this plant. Solvent extraction method was employed to isolate compounds from the ethyl acetate and ethyl methyl ketone fractions of the hydro-ethanolic (90%) extract of the fruits of the locally grown C. colocynthis. Structures of the isolated compounds were elucidated by spectroscopic means. Two cucurbitacin glucosides, 2-O-β-D-glucopyranosylcucurbitacin I and 2-O-β-D-glucopyranosylcucurbitacin L were isolated and identified.

Keywords


Citrullus colocynthis, Cucurbitaceae, Cucurbitacin I, Cucurbitacin L.