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Anthelmintic Activity of Hiptage benghalensis (L) Kurz Leaves


Affiliations
1 Varadvinayak Sankul, Flat No-1, Bajrang Chawk, N-8, CIDCO, Aurangabad-431005, India
2 Gangamai College of Pharmacy, Nagaon, Dhule, India
3 Science College, Nagaon, Dhule (M.S.), India
4 KYDSCT,s College of Pharmacy, Sakegaon, Jalgaon (M.S.), India
     

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Worm infestation is one of the major global public health problems, more so in tropical countries. Worms can cause various GI and general symptoms. In addition some of them can cause blood lose, nutritional deficiencies. Helminthiasis is among the most important animal health problems. The disease is highly prevalent particularly in developing countries. In present study Aqueous and ethanolic extract of Hiptage benghalensis (L) kurz, belonging to family Malpighiaceae leaves were investigated for anthelmintic activity. The extracts were used in concertrations of 5, 10 and 25mg/ml and the process involves determination of time of paralysis and time of death of Pheritima posthuma (earth worm). Among the two extracts tested, aqueous extract showed more potent activity against the worm when compared with standard drug Piperazine citrate.

Keywords

Anthelmintic, Hiptage Bengalensis, Piperazine Citrate, Aqueous Extract.
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  • Anthelmintic Activity of Hiptage benghalensis (L) Kurz Leaves

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Authors

S. V. Chordiya
Varadvinayak Sankul, Flat No-1, Bajrang Chawk, N-8, CIDCO, Aurangabad-431005, India
R. B. Pimprikar
Gangamai College of Pharmacy, Nagaon, Dhule, India
S. B. Yeshwante
Gangamai College of Pharmacy, Nagaon, Dhule, India
Tanvir Shaikh
Gangamai College of Pharmacy, Nagaon, Dhule, India
P. N. Patil
Science College, Nagaon, Dhule (M.S.), India
M. K. Kale
KYDSCT,s College of Pharmacy, Sakegaon, Jalgaon (M.S.), India
B. M. Firke
KYDSCT,s College of Pharmacy, Sakegaon, Jalgaon (M.S.), India

Abstract


Worm infestation is one of the major global public health problems, more so in tropical countries. Worms can cause various GI and general symptoms. In addition some of them can cause blood lose, nutritional deficiencies. Helminthiasis is among the most important animal health problems. The disease is highly prevalent particularly in developing countries. In present study Aqueous and ethanolic extract of Hiptage benghalensis (L) kurz, belonging to family Malpighiaceae leaves were investigated for anthelmintic activity. The extracts were used in concertrations of 5, 10 and 25mg/ml and the process involves determination of time of paralysis and time of death of Pheritima posthuma (earth worm). Among the two extracts tested, aqueous extract showed more potent activity against the worm when compared with standard drug Piperazine citrate.

Keywords


Anthelmintic, Hiptage Bengalensis, Piperazine Citrate, Aqueous Extract.