GC-MS Analysis of Phyto-Constituents and Antimicrobial Activity of Hexane Extract of Lanatana Camara Linn.

Nature has been a source of medical agents for thousands of years. Lantana camara linn., family verbenaceae, commonly known as wild sage, is a flowering shrubs native of tropical America and is cultivated throughout the world as an ornamental . The plant based traditional medicine system continues to play an essential role in health care, with about 80% of the world inhabitants. The plant leaves contain a number of medicinally important compounds. The present study was carried out to identify the phytoconstituents and evaluate antimicrobial activity of hexane extract of Lantana camara leaves. The mass spectra of these phytoconstituents were matched with the database available at National Institute of Standard and Technology (NIST) library. The Gas chromatography and Mass spectrometry analysis of terpenes, alkaloids, flavonoids, glycosides, protein etc. lead to identification of 18 compounds. This analysis revealed that the phytoconstituents fraction shows high peak, mainly 2,2,4-trimethyl-3(3,8,12,16-tetramethyl-heptadeca-3,7,11,15-tetraenyl)-cyclohexanol, Cholesta-2,4-diene. The research reveals the potential of hexane extract of Lantana camara leaves as a good source of terpenes, steroids that justify the use of this plant for its various ailments by traditional practitioners. It is used for healing of gastric ulcer, respiratory infections and antipyretic. Lantana camara have therapeutic potential due to the presence of natural agents, Majority of their activity is due to bioactive compounds viz. flavones, isoflavones, flavonoids, anthocyanins, coumarins, lignans, catechins, isocatechins, alkaloids, tannin, saponins and triterpenoids. Bioactive substance from this plant can therefore be employed in the formulation of antimicrobial agents for the treatment of various microbial infection.