Research Journal of Pharmacognosy and Phytochemistry

M. Murugan ¹, C. Uma Maheswara Reddy ², S. Vedhapal Jeyamani ¹, D. Babu Ananth ¹, K. Umasankar ¹

Affiliations
1 Maharaji College of Pharmacy, Chennai-600 090, IN
2 Sri Ramachandra College of Pharmacy, Chennai 600 116, IN

Abstract

Ethanolic leaf extract of Erythrina varigata was carried out using soxhlet apparatus. The extract was evaluated for preliminary phytochemical studies, acute toxicity studies and hypoglycemic activity. Acute toxicity study revealed that the ethanolic leaf extract even at high dose (2000mg/ kg) produced no death and found to be safe. The hypoglycemic activity was evaluated in normal and alloxan induced diabetic mice. The chloroform fraction of the leaf extract was found to possess significant hypoglycemic activity when compared to standard Glibenclamide.

Keywords

Erythrina varigata, Hypoglycemic Activity, Diabetes Mellitus.

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