Research Journal of Pharmacognosy and Phytochemistry

Yogesh Shivhare ¹, Priya Singh ², K. K. Patel ², Prashant Soni ²

Affiliations
1 30, Gomati Colony, Nehru Nagar, Bhopal (M.P.), IN
2 Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), IN

Abstract

In-vitro antioxidant activity of petroleum ether extract of Trichosanthes dioica was determined by DPPH free radical scavenging assay, Reducing power assay, Nitric oxide scavenging activity, Hydrogen peroxide radical scavenging activity using ascorbic acid as a standard. The IC₅₀ values were calculated for all the models in order to evaluate the antioxidant efficiency of Trichosanthes dioica extract. In all the testing a significant correlation existed between concentration of the extract and % inhibition of free radicals. Obtained results clearly indicated that petroleum ether extract of Trichosanthes dioica possesses significant antioxidant potential as compared with standard.

Keywords

Trichosanthes dioica, Nitric Oxide, % Inhibition.

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Yogesh Shivhare ¹, Priya Singh ², Radhika Gadekar ², Prashant Soni ³

Affiliations
1 30, Gomati Colony, Nehru Nagar, Bhopal (M.P.), IN
2 Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), IN
3 Dept. of Pharmacognosy, RKDF College of Pharmacy, Bhopal (M.P.), IN

Abstract

There is escalating curiosity in the fitness and wellness profit of herbs and botanicals. This is with good reason as plants and their extracts have enormous prospective for the management and treatment of different diseases. There are an increasing number of studies purporting antioxidant effects with conventional medicines. The present review is planned to deliver an overview of the current knowledge surrounding the use of herbal medicines as antioxidants and also to identify the research needs in this area.

Keywords

Botanicals, Antioxidants, Plants.

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