Research Journal of Pharmacology and Pharmacodynamics

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

In Vitro Anthelmintic Activity of Medicinal Plants against Pheretima posthuma


Affiliations
1 Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli - Miraj Road, Sangli. 416416, India
2 Rajarambapu College of Pharmacy, Kasegaon, Sangli, India
     

   Subscribe/Renew Journal


In this study, in vitro activity of were conducted to determine the possible anthelmintic activity of different solvent extracts like aqueous extract of leaves of cajanus cajan Linn, methanolic extract of leaves of vitex negundo Linn, Ethanolic extract of bark of Euphorbia tirucalli Linn and ethyl acetate extract of leaves of synadiium grantii Linn, methanolic extract of leaves of Euphorbia nerrifolia Linn against Indian worm Pheretima posthuma. With regard to effect of extract of Euphorbia tirucalli Linn, Euphorbia nerrifolia Linn, cajanus cajan Linn showed significant action on earthworm, vitex negundo Linn showed moderate activity. All the extracts were found not only to paralyse (vermifuse) but also death (vermicidal) except ethyl acetate extract of synadiumm graantii.

Keywords

Anthelminitic Activity, Pheretima posthuma, Euphorbia nerrifolia Linn. Euphorbia tirucalli Linn, Synadiium grantii Linn, cajanus cajan Linn, vitex Negundo Linn.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Tagboto S., Townson S., Antiparasitic properties of medicinal and other naturally occurring products, Adv Parasitol, , 2001, 50, 199-295.

  • Tadessae Eguale, Mirutse Giday, In-vitro anthelmintic activity of three medicinal plants against Haemonchus contortus. International journal of green pharmacy, 2009, 29-34.

  • Duke, J.A., "Handbook of legumes of world economic importance", Plenum Press, New York, 1981.

  • Rashik, A.M., A. Shukla, G.K. Patnaik, B.N. Dhawan and D.K Kulshrestha, Wound healing activity of latex of Euphorbia neriifolia Linn. Indian J. Pharmacol., 1996, 28(2): 107-109.

  • Lanthers MC, Fleurentin J, Dorfman P, Mortier F, Pelt JM. Analgesis, antipyretic and anti- inflammatory properties of Euphorbia hirta. Planta Med, 1991; 57(3):225-231.

  • Kirtikar, KR.; Basu, BD., Indian medicinal plants, Vol 3, 1975. pp 2204

  • Nair CK, Mohenan N. Medicinal plants in India with special reference to Ayurveda. NAG Publisher, Delhi, India 1998.

  • Telang RS, Chatterjee S, Varshneya C. Studies on analgesic and antiinflammatory activities of Vitex negundo Linn. Indian J Pharmacol 1999; 31: 363–366.

  • Jana U, Chattopadhyay RN, Shaw BP. Preliminary studies on anti-inflammatory activity of Zingiber officinale , Vitex negundo Linn and Tinospora Cordifolia (willd) miers in albinorats. Indian J Pharmacol 1999; 31: 232–233.

  • Ravishankar B, Bhaskaran NR, Sasikala CK. Pharmacological evaluation of Vitex negundo (Nirgundi) leaves. Bull Med Ethno Bot Res 1985; VI (1): 72–92.

  • Gupta M, Mazumder UK, Bhawal SR. CNS activity of Vitexnegundo Linn in mice. Indian J Exp Biol 1999; 37; 143–146.

  • Avadhoot Y, Rana AC. Hepatoprotective effect of Vitex negundo against carbon tetrachloride induced liver damage.Arch Pharm Res 1991; 14(1): 96–98.

  • Nair AM and Saraf MN. Inhibition of antigen and compound 48/80 induced contraction of guinea pig trachea by ethanolic extract of the leaves of Vitex negundo Linn. Indian J Pharmacol 1995; 27: 230– 233.

  • Kuvar SD and Bapat UC medicinal plant used by kokani tribals of nasik district Maharashtra to cure cuts and wounds. Indian journal of traditional knowledge VOL.9(1) , 2010, pp,144-115.

  • Uma Shankar Sharma,In vitro anthelmintic activity of Murraya koenigii Linn leaves extract. International Journal of Pharma and Bio Sciences Vol.1 (3) 2010 pg no. 1-4.


Abstract Views: 470

PDF Views: 2




  • In Vitro Anthelmintic Activity of Medicinal Plants against Pheretima posthuma

Abstract Views: 470  |  PDF Views: 2

Authors

R. S. Ghodake
Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli - Miraj Road, Sangli. 416416, India
N. S. Patole
Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli - Miraj Road, Sangli. 416416, India
S. B. Patil
Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli - Miraj Road, Sangli. 416416, India
N. S. Naikwade
Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli - Miraj Road, Sangli. 416416, India
C. S. Magdum
Rajarambapu College of Pharmacy, Kasegaon, Sangli, India

Abstract


In this study, in vitro activity of were conducted to determine the possible anthelmintic activity of different solvent extracts like aqueous extract of leaves of cajanus cajan Linn, methanolic extract of leaves of vitex negundo Linn, Ethanolic extract of bark of Euphorbia tirucalli Linn and ethyl acetate extract of leaves of synadiium grantii Linn, methanolic extract of leaves of Euphorbia nerrifolia Linn against Indian worm Pheretima posthuma. With regard to effect of extract of Euphorbia tirucalli Linn, Euphorbia nerrifolia Linn, cajanus cajan Linn showed significant action on earthworm, vitex negundo Linn showed moderate activity. All the extracts were found not only to paralyse (vermifuse) but also death (vermicidal) except ethyl acetate extract of synadiumm graantii.

Keywords


Anthelminitic Activity, Pheretima posthuma, Euphorbia nerrifolia Linn. Euphorbia tirucalli Linn, Synadiium grantii Linn, cajanus cajan Linn, vitex Negundo Linn.

References