Research Journal of Pharmacology and Pharmacodynamics

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Glycine max: The Antioxidant and Anti-Hyperlipidemic Nutraceutical


Affiliations
1 Prin. K M Kundnani College of Pharmacy, 23, Jote Joy Bldg., Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai-400005
2 Prin. K M Kundnani College of Pharmacy, 23, Jote Joy Bldg., Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai-400005, India
     

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The nutraceutical industry has seen a great boom in the recent years as a result of the consumers seeking the convenient "healthful" solution in their diet. Amongst the various candidates of the nutraceutical world the everyday soybean has become a great nutraceutical today. In view of the importance gained by soybeans (Glycine max Family: Leguminosae) studies were carried out on the seeds of soybean. To evaluate its nutraceutical claims, antioxidant and anti-hyperlipidemic evaluations were carried out on the extracts obtained from the seeds of Glycine max. With an increase in the health reports relating free radicals and high lipid levels to an array of disease conditions, there has been a search for a safer solution from the nutraceutical world as a support to the conventional therapy. In the current study, the free radical scavenging activity was carried out using the DPPH method whereas the diet induced hyperlipidemia model in hamsters was used to evaluate the antihyperlipidemic activity. Both the studies yield results that support the current position of soybeans in the nutraceutical world.

Keywords

Glycine max, Soybean, Antioxidant, Anti-Hyperlipidemic.
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  • Hymowitz T, Soybeans: The Success Story, Advances in New Crops, Timber Press, Oregon, 1990.

  • Hymowitz T. On the Domestication of the Soybean. Economic Botany. 1970; 24 (4): 408-421

  • Mateos-Aparicio I et al. Soybean, a promising health source. Nutricion Hospitalaria. 2008; 23(4): 305-312

  • Brandon DL, Bates AH and Friedman L. Immunoassays for Bowman-Birk and Kunitz Soybean Trypsin Inhibitors in Infant Formula. Journal of Food Science. 2004; 69 (1): 11-15

  • Hu J et al. Soyasaponin I and Sapongenol B Have Limited Absorption by Caco-2 Intestinal Cells and Limited Bioavailability in Women. Journal of Nutrition. 2004, 134: 1867-1873

  • Rajpal V. Standardization of Botanicals. Eastern Publishers, New Delhi, India, 2005.

  • Adams MR et al. Soy protein containing isoflavones reduces the size of atherosclerotic plaques without affecting coronary artery reactivity in adult male monkeys. The Journal of Nutrition. 2005; 135(12): 2852-2856

  • Banavalikar MM, Suthar AC and Biyani MK. Pharmacological activities of Genistein, an isoflavone from soy (Glycine max): part II-anti-cholesterol activity, effects on osteoporosis & menopausal symptoms. Indian journal of experimental biology. 2001; 39(6): 520-525

  • Dixon RA and Ferreira D. Genistein. Phytochemistry. 2002; 60(3): 205-211

  • Suthar AC, Banavalikar MM and Biyani MK, Pharmacological activities of Genistein, an isoflavone from soy (Glycine max): part I--anti-cancer activity. Indian Journal of Experimental Biology. 2001; 39(6): 511-519

  • DeFelice SL. Nutraceuticals: Developing, Claiming and Marketing Medical Foods. Marcel Dekker Inc., New York, 1998.

  • Patil S, Jolly CI and Narayanan S. Free radical scavenging activity of Acacia catechu and Rotula aquatica: Implications in cancer therapy. Indian Drugs. 2003; 40(6): 328-332

  • Vogel HG. Drug Discovery and Evaluation. Springer-Verlag Berlin Heidelberg, Germany, 2002.

  • Xiao CW. Health effects of soy proteins and isoflavones in humans. The Journal of Nutrition. 2008; 138(6): 1244S-9S

  • Bagchi K and Puri S. Free radicals and antioxidants in health and disease. Eastern Mediterranean Health Journal. 1998; 4(2): 350-360


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  • Glycine max: The Antioxidant and Anti-Hyperlipidemic Nutraceutical

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Authors

Manasi Nabar
Prin. K M Kundnani College of Pharmacy, 23, Jote Joy Bldg., Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai-400005
Swati Patil
Prin. K M Kundnani College of Pharmacy, 23, Jote Joy Bldg., Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai-400005, India

Abstract


The nutraceutical industry has seen a great boom in the recent years as a result of the consumers seeking the convenient "healthful" solution in their diet. Amongst the various candidates of the nutraceutical world the everyday soybean has become a great nutraceutical today. In view of the importance gained by soybeans (Glycine max Family: Leguminosae) studies were carried out on the seeds of soybean. To evaluate its nutraceutical claims, antioxidant and anti-hyperlipidemic evaluations were carried out on the extracts obtained from the seeds of Glycine max. With an increase in the health reports relating free radicals and high lipid levels to an array of disease conditions, there has been a search for a safer solution from the nutraceutical world as a support to the conventional therapy. In the current study, the free radical scavenging activity was carried out using the DPPH method whereas the diet induced hyperlipidemia model in hamsters was used to evaluate the antihyperlipidemic activity. Both the studies yield results that support the current position of soybeans in the nutraceutical world.

Keywords


Glycine max, Soybean, Antioxidant, Anti-Hyperlipidemic.

References