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Nagpal, Manju
- Study of Anti-Inflammatory Potential of Ethanolic Fraction of Seeds of Ocimum basilicum Linn
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Authors
Affiliations
1 Rajendra Institute of Technology and Sciences, 4th mile stone, Hisar Road, Sirsa - 125055, IN
2 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
1 Rajendra Institute of Technology and Sciences, 4th mile stone, Hisar Road, Sirsa - 125055, IN
2 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 2 (2009), Pagination: 79-81Abstract
In the present study the ethanolic fraction of seeds of the plant Ocimum basilicum Linn. was taken and its anti-inflammatory potential was evaluated using carrageenan and formalin induced rat paw edema. The effect on chronic phase of inflammation was also studied using cotton pellet granuloma technique. The increase in paw thickness was measured using digital vernier caliper after 1,2,3 and 4 h of injection. Ethanolic fraction of the seeds of the plant at dose of 400 mg/Kg significantly inhibited acute phase of inflammation. The decrease in the weight of granuloma was also found by ethanolic fraction of the seeds at same dose. The study reveals that the ethanolic fraction of seeds of Ocimum basilicum Linn. possesses significant anti-inflammatory activity.Keywords
Anti-Inflammatory, Carrageenan, Formalin, Granuloma.
References
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- Gastroesophageal Reflux Disease: Pathophysiology and Treatments Available
Abstract Views :208 |
PDF Views:1
Authors
Affiliations
1 Rajendra Institute of Technology and Sciences, Sirsa Haryana, IN
2 Chitkara School of Pharmaceutical Sciences, Chitkara University, Barotiwala HP, IN
3 NCRD's Sterling Institute of Pharmacy, Navi Mumbai, IN
1 Rajendra Institute of Technology and Sciences, Sirsa Haryana, IN
2 Chitkara School of Pharmaceutical Sciences, Chitkara University, Barotiwala HP, IN
3 NCRD's Sterling Institute of Pharmacy, Navi Mumbai, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 2 (2010), Pagination: 160-164Abstract
Gastroesophageal reflux disease (GERD) is primarily a motility disorder. Escape of gastric contents into the esophagus occurs as a consequence of an incompetent gastroesophageal barrier. This barrier is weakened in the presence of an abnormally functioning Lower Esophageal Sphincter (LES). This review is focused on the epidemiology, pathophysiology and treatments of gastro-oesophageal reflux disease.Keywords
Reflux, Proton Pump Inhibitors, H2 Receptor Antagonists, Radiofrequency.References
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