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Rachid, Rouabhi
- Toxic Effects of Acrolyc Denture Teeth Resin, Lucitone 119 on Animal Model: Rats Wistar
Abstract Views :252 |
PDF Views:2
Authors
Bouaricha Houda
1,
Grifi Fatiha
2,
Berrebbah Houria
1,
Tadjine Aicha
1,
Rouabhi Rachid
3,
Djebar Mohammed-Réda
1
Affiliations
1 Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, DZ
2 Annaba University, Annaba, 23000, DZ
3 N.& L. S. Department, Tebessa University, Tebessa, 12000, DZ
1 Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, DZ
2 Annaba University, Annaba, 23000, DZ
3 N.& L. S. Department, Tebessa University, Tebessa, 12000, DZ
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 36-40Abstract
This study examines the potential toxic effects of lead compounds of an acrylic resin used in the manufacture of dental bases: the LUCITONE 119. The resin treatment is swallowed by diluting the compound in the drinking water of female Wistar rats. After treatment for 07 days and 21 days, average weights of animals and two organs (liver and spleen) are determined. Meanwhile, cellular blood components (red cells, hemoglobin, hematocrit, platelets, lymphocytes, monocytes and granulocytes) and haematological parameters (MCV, MCH and MCHC) were measured. The results show a disturbance in average weight of rats associated with that of the two organs involved (liver and spleen). Biochemical assays show a significant hematotoxicity mainly on platelets, hematocrit and leukocyte lineage.Keywords
Acrylic Resin, Lucitone119, Wistar Rats, Hematological Toxicity, Blood.
References
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- Mac Cabe, J.F. and R.M. Basker, 1976. Tissue sensitivity to acrylic resin. A method of measuring the residual monomer content and its clinical application. Br. Dent. J., 18: 347-50.
- Barclay, S.C., A. Forsyth, D.H. Felix and I.B. Watson, 1999. Case report hypersensitivity to denture materials. Br. Dent. J., 187: 350-352.
- Nagem-Filho, H., N.J. Chiodi and P.A. Araujo, 1973. Biocompatibility of acrylic resins implants in connective tissue. Estomatol&Cult, 7: 120-3.
- Kallus, T., 1984. Evaluation of the toxicity of denture base polymers after subcutaneous implantation in guinea pigs. J. Prosthet. Dent., 52: 126-134.
- Wennberg, A., G. Hasselgren and L. Tronstad, 1979. A method for toxicity screening of biomaterials using cells cultured on millipore filters. J. Biomed Mater Res., 13: 109-120.
- Cimpan, M.R., R. Matre, L.I. Cressey, B. Tysnes, S.A. Lie and B.T. Gjertsen, 2000. The effect of heat- and auto-polymerized denture base polymers on clonogenicity, apoptosis and necrosis in fibroblasts: denture base polymers induce apoptosis and necrosis. Acta Odontol Scand, (58): 217-28.
- Forsberg, K. and S.Z. Mansdorf, 2002. Quick selection guide to chemical protective clothing. NJ, États-Unis: John Wiley&Sons, pp: 71.
- CIRC/IARC, 1994. Methyl Methacrylate. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Lyon: Centre international de recherche sur le cancer; (60): 445-474.
- Kalipicilar, B., L. Karaagacliogue and U. Hasanreisoglu, 1991. Evaluation of the level of residual monomer in acrylic denture base materials having different polymerization properties. Oral Rehabil., pp: 40-339.
- Tomenson, J.A., A.V. Carpenter and miology literature on the potential cancer risk of methylmethacrylate. Int.Arch.Occup. Env. Health. (78): 603-612.
- Golbabaei, F., M. Mamdouh, K.N. Jelyani and S.J. Shahtaher, 2005. Exposure to methyl methacrylate and subjective symptoms among dental technicians. Inter- national J. Occupational Safety and Ergonomics (JOSE). Tehran, Iran, (3): 283-289.
- Harleman, J.H., 2000. Approaches to the identification and recording of finding in the lymphoreticular organs indicative for immunotoxicity in regulatory type toxicity studies. Toxicology and applied Pharmacol., (42): 213-219.
- Rosenberg, N., 2001. Allergie respiratoire aux acrylates, méthacrylates et no acrylates. Documents pour le médecin du travail. J. Dent., (28): 411-418.
- Tadjine, A., H. Berrebbah et and C. Arnaud, 2008. Toxicité des poussières rejetées par le complexe sidérurgie d'Annaba sur quelques paramètres hématologiques du lapin: Revue Environnement, Risques et Santé., 17(3): 23-25.
- Makarov, I.A., 1984. Sexual disorders in male workers occupationally exposed to methylmetacrylate and vinylchloride. GigTr Prof Zabol. Russia, National Library of Med., (6): 19-23.
- Widley, J. and H. Sons, 2006. Kirk-othmer- Encyclopediatchemicaltechnology, 5th Ed. New York; (16): 227-270.
- Turell, A.J., 1966. Allergy to denture-base materials- Fallacy or reality. Br. Dent. J., pp: 120-415.
- Danilewiez-stysiak, G., 1971. Allergy as a cause of denture sore mouth. J. Prosthet. Dent., (16): 18-25.
- Bezzon, O.L., 1993. Allergic sensivity to several base metals: a clinical report. J. Prosthet. Dent., (69): 243-244.
- Cincinnati, M. and L. Ohio, 2000. Prosthetic base denture and allergy Dent, 20: 17-20. M.A. Pemberton, 2005. Critical review of the epide
- Correlation between Changes in Biochemical Roots of Wheat (Triticum durum desf) and Stress Induced by some Regimes Fertilizer NPK
Abstract Views :186 |
PDF Views:2
Authors
Bouchelaghem Sabrina
1,
Djebar Mohammed-Réda
1,
Rouabhi Rachid
2,
Ramdani Kamel
1,
Berrebbah Houria
3
Affiliations
1 Laboratory of Cell Toxicology. Badjimokhtar University Annaba, 23000, Annaba, DZ
2 Nature and Life Sciences Department, Tebessa University, DZ
3 Nature and life Sciences department,Tebessa University, DZ
1 Laboratory of Cell Toxicology. Badjimokhtar University Annaba, 23000, Annaba, DZ
2 Nature and Life Sciences Department, Tebessa University, DZ
3 Nature and life Sciences department,Tebessa University, DZ
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 47-51Abstract
We studied the physio-biochemical parameters of the wheat ischolar_mains (Tritium durum Desf), in the water content (TE), total protein levels (TPL), carbohydrate (TCH) proline (TP), Malondialdehyde (MDA), on the one hand and enzyme activities catalase (CAT) and ascorbate-Perroxydase (APX) on the other hand, with four fertilizer regimes: 0.5: 01: 01, 0.5: 02: 01, 0.5: 03: 01 and 0.5: 04: 01g/propagator NPK. Our results show that the maximum content of water is obtained with the regime. 0.5: 01: 01g/propagator NPK. Total protein and the average maximum with 0.5 proline proved: 02: 01, 0.5: 03: 01 and 0.5: 04: 01g / hotbed of NPK. It records the total carbohydrate highest respectively 0.5: 02: 01; 0.5: 03: 01 and 0.5: 04: 01g/hotbed NPK. The activities of enzymes catalase (CAT), ascorbate peroxidase (APX), were measured simultaneously with the average rates of malondialdehyde (MDA) and the parameters as indicators of cellular disorders. The results obtained show that the schemes 0.5: 02: 01 and 0.5: 03: 01 and 0.5: 04: 01g/Propagator NPK are capable of generating oxidative stress expressed through stimulation of enzyme activity CAT and APX and resulted in a significant increase in the average rate of MDA. This does not seem to be the case for regime 0.5: 01: 01g/Propagator NPK. Our study thus demonstrates the existence of a positive correlation between water content, total protein, carbohydrate, proline, MDA, CAT and APX in ischolar_mains of wheat with three fertilizer regimes 0.5: 02: 01; 0.5: 03: 01 and 0.5: 04: 01g/Propagator NPK. Our results suggest a possible apparent toxicity may be associated with some phosphate fertilizers.Keywords
NPK, Wheat, Fertilizer, Toxicity, Roots.References
- Elalaoui A.C., 2007. Fertilisation minérale des cultures. Les éléments minéraux secondaires et oligoof éléments. Bull. Mens. Inf. PNTTA, 156: 1-4.
- Union des Industries Chimiques, (UIC); 2006. Céréales et oligoéléments. Revue Chimie, pp: 11.
- Pain, A.K., 1965. Effet de l'engrais NPK et de leurs combinaisons sur le rendement et la Valeur nutritive des mûriers. Indian J. Seric., 4: 1-8.
- Kasiviswanathan, K., S. Krishnaswamiet and P.C. Chowdhury, 1979. Études à long terme sur la variété, l'espacement et la fertilisation azotée pour l'amélioration du rendement potentiel de mûrier. Indian J. Seric., 18: 23-29.
- Islam, R., M.A. Bari et and Z. Ahsan, 1982. Effet de différents niveaux d'engrais sur les feuilles rendement du mûrier à la condition irriguée. Bangladesh J. Agric., 6(7): 25-30.
- Islam, R., M.A. Bari et. and R. Ali, 1985. Effet de l'azote, du phosphore et de potassium et leur combinaison sur le rendement en feuilles de mûrier. J. Asiatic. Soc. Bangladesh. (Sc.). 11: 1-5.
- Mahmoud, L.M., 2009. Effet de l'eau, du stress et de la fertilisation NPK sur la croissance et le contenu en résine Grindeliacamporum Greene. Bangladesh J. Agril. Res., 34(3): 435-442.
- Kayode, G.O., 2005. Effects of NPK fertilizer on tuber yield, starch content and dry matter accumulation of white guinea yam (Dioscorearotundata) in a forest alfisol of south western Nigeria. Exp. Agr., 21: 389-393.
- Lene, K.C., S.K. Upadhyaya, B. Jahn, D.C. Slaughter, E. Tan and D. Hills, 2007. Determining the Influence of Water Deficiency on NPK Stress Discrimination in Maize using Spectral and Spatial Information. Pre. Agr., 6: 539-550.
- Khaldi F., H. Djebar, R. Rouabhi and M.R. Djebar, 2009. Cellular Response of a Pollution Bioindicator Model (Ramalinafarinacea) Following Treatment with Fertilizer (NPKs). Am. Eur. J. Toxicol. Sci., 1(2): 69-73.
- Monneveux, P.H. and et M. Nemmar, 1986. Contribution à l'étude de la résistance à la sécheresse chez le blé tendre. Etude de l'accumulation de la proline au cours du cycle de développement. Agronomie. pp: 1-17.
- Bradford, M., 1976. A Rapid and Sensitive Method for the quantification of microgram quantities of protein utilizing the principal of protein-Dye Binding. Analytical Biochem. 72: 248-254.
- Troll, W. and J. Lindesley, 1955. A photometric for the determination proline. J. Biochem. 215: 655-660.
- Chai, T.T., N.M. Fadzillah, M. Kusnanand and M. Mahmood, 1999. Induction of oxidative stress in Musa sp. (variety Berangan) by paraquat treatments. in Proceedings of the First national banana seminar (Z. Wahab, M.T.M. Mohamed, S.K. Daud, N.M. Fadzillahand M. Mahmood, eds). Universiti Putra Malasia, Universiti Malaya and MARDI, Malaysia. pp: 186-190.
- Nakano, Y. and K. Azada, 1987. Purification of ascorbate peroxidase in spinach chloroplasts: its inactivation in ascorbate depleted medium and reactivation by mono dehydro ascorbate radical. Plant Cell. Physiol., 28: 131-140.
- Cakmak, I. and W.J. Horst, 1991. Effect of aluminum on lipid peroxidation, superoxide dismutase, catalase and peroxidase activities in ischolar_main tips of soybean (glycine max). Physiol. Plant. 83: 463-468.
- Miah, M.A.B., 1989. Des études sur la croissance et le rendement du mûrier (Morus alba L.). Ph.D. Thesis. Université de Rajshahi, Bangladesh.
- Quader, M.A., M.A. Qayyum, A.A. Sarkar, M.A. Rab et. and S.U. Ahmed, 1992. Bull. Sericult.
- Sbartai H., R. Rouabhi, I. Sbartai, H. Berrebbah and M.R. Djebar, 2007. Induction of anti-oxidative enzymes by cadmium stress in tomato (Lycopersiconesculentum) African J. Plant Sci., 2(8): 072-076.
- Correlation between Changes in Biochemical Roots of Wheat (Triticum durum desf) and Stress Induced by some Regimes Fertilizer NPK
Abstract Views :208 |
PDF Views:2
Authors
Bouchelaghem Sabrina
1,
Djebar Mohammed-Réda
1,
Rouabhi Rachid
2,
Ramdani Kamel
1,
Berrebbah Houria
3
Affiliations
1 Laboratory of Cell Toxicology. Badjimokhtar University Annaba, 23000, Annaba, DZ
2 Nature and Life Sciences Department, Tebessa University, DZ
3 Nature and life Sciences department,Tebessa University, DZ
1 Laboratory of Cell Toxicology. Badjimokhtar University Annaba, 23000, Annaba, DZ
2 Nature and Life Sciences Department, Tebessa University, DZ
3 Nature and life Sciences department,Tebessa University, DZ
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 47-51Abstract
We studied the physio-biochemical parameters of the wheat ischolar_mains (Tritium durum Desf), in the water content (TE), total protein levels (TPL), carbohydrate (TCH) proline (TP), Malondialdehyde (MDA), on the one hand and enzyme activities catalase (CAT) and ascorbate-Perroxydase (APX) on the other hand, with four fertilizer regimes: 0.5: 01: 01, 0.5: 02: 01, 0.5: 03: 01 and 0.5: 04: 01g/propagator NPK. Our results show that the maximum content of water is obtained with the regime. 0.5: 01: 01g/propagator NPK. Total protein and the average maximum with 0.5 proline proved: 02: 01, 0.5: 03: 01 and 0.5: 04: 01g / hotbed of NPK. It records the total carbohydrate highest respectively 0.5: 02: 01; 0.5: 03: 01 and 0.5: 04: 01g/hotbed NPK. The activities of enzymes catalase (CAT), ascorbate peroxidase (APX), were measured simultaneously with the average rates of malondialdehyde (MDA) and the parameters as indicators of cellular disorders. The results obtained show that the schemes 0.5: 02: 01 and 0.5: 03: 01 and 0.5: 04: 01g/Propagator NPK are capable of generating oxidative stress expressed through stimulation of enzyme activity CAT and APX and resulted in a significant increase in the average rate of MDA. This does not seem to be the case for regime 0.5: 01: 01g/Propagator NPK. Our study thus demonstrates the existence of a positive correlation between water content, total protein, carbohydrate, proline, MDA, CAT and APX in ischolar_mains of wheat with three fertilizer regimes 0.5: 02: 01; 0.5: 03: 01 and 0.5: 04: 01g/Propagator NPK. Our results suggest a possible apparent toxicity may be associated with some phosphate fertilizers.Keywords
NPK, Wheat, Fertilizer, Toxicity, Roots.References
- Elalaoui A.C., 2007. Fertilisation minérale des cultures. Les éléments minéraux secondaires et oligoof éléments. Bull. Mens. Inf. PNTTA, 156: 1-4.
- Union des Industries Chimiques, (UIC); 2006. Céréales et oligoéléments. Revue Chimie, pp: 11.
- Pain, A.K., 1965. Effet de l'engrais NPK et de leurs combinaisons sur le rendement et la Valeur nutritive des mûriers. Indian J. Seric., 4: 1-8.
- Kasiviswanathan, K., S. Krishnaswamiet and P.C. Chowdhury, 1979. Études à long terme sur la variété, l'espacement et la fertilisation azotée pour l'amélioration du rendement potentiel de mûrier. Indian J. Seric., 18: 23-29.
- Islam, R., M.A. Bari et and Z. Ahsan, 1982. Effet de différents niveaux d'engrais sur les feuilles rendement du mûrier à la condition irriguée. Bangladesh J. Agric., 6(7): 25-30.
- Islam, R., M.A. Bari et. and R. Ali, 1985. Effet de l'azote, du phosphore et de potassium et leur combinaison sur le rendement en feuilles de mûrier. J. Asiatic. Soc. Bangladesh. (Sc.). 11: 1-5.
- Mahmoud, L.M., 2009. Effet de l'eau, du stress et de la fertilisation NPK sur la croissance et le contenu en résine Grindeliacamporum Greene. Bangladesh J. Agril. Res., 34(3): 435-442.
- Kayode, G.O., 2005. Effects of NPK fertilizer on tuber yield, starch content and dry matter accumulation of white guinea yam (Dioscorearotundata) in a forest alfisol of south western Nigeria. Exp. Agr., 21: 389-393.
- Lene, K.C., S.K. Upadhyaya, B. Jahn, D.C. Slaughter, E. Tan and D. Hills, 2007. Determining the Influence of Water Deficiency on NPK Stress Discrimination in Maize using Spectral and Spatial Information. Pre. Agr., 6: 539-550.
- Khaldi F., H. Djebar, R. Rouabhi and M.R. Djebar, 2009. Cellular Response of a Pollution Bioindicator Model (Ramalinafarinacea) Following Treatment with Fertilizer (NPKs). Am. Eur. J. Toxicol. Sci., 1(2): 69-73.
- Monneveux, P.H. and et M. Nemmar, 1986. Contribution à l'étude de la résistance à la sécheresse chez le blé tendre. Etude de l'accumulation de la proline au cours du cycle de développement. Agronomie. pp: 1-17.
- Bradford, M., 1976. A Rapid and Sensitive Method for the quantification of microgram quantities of protein utilizing the principal of protein-Dye Binding. Analytical Biochem. 72: 248-254.
- Troll, W. and J. Lindesley, 1955. A photometric for the determination proline. J. Biochem. 215: 655-660.
- Chai, T.T., N.M. Fadzillah, M. Kusnanand and M. Mahmood, 1999. Induction of oxidative stress in Musa sp. (variety Berangan) by paraquat treatments. in Proceedings of the First national banana seminar (Z. Wahab, M.T.M. Mohamed, S.K. Daud, N.M. Fadzillahand M. Mahmood, eds). Universiti Putra Malasia, Universiti Malaya and MARDI, Malaysia. pp: 186-190.
- Nakano, Y. and K. Azada, 1987. Purification of ascorbate peroxidase in spinach chloroplasts: its inactivation in ascorbate depleted medium and reactivation by mono dehydro ascorbate radical. Plant Cell. Physiol., 28: 131-140.
- Cakmak, I. and W.J. Horst, 1991. Effect of aluminum on lipid peroxidation, superoxide dismutase, catalase and peroxidase activities in ischolar_main tips of soybean (glycine max). Physiol. Plant. 83: 463-468.
- Miah, M.A.B., 1989. Des études sur la croissance et le rendement du mûrier (Morus alba L.). Ph.D. Thesis. Université de Rajshahi, Bangladesh.
- Quader, M.A., M.A. Qayyum, A.A. Sarkar, M.A. Rab et. and S.U. Ahmed, 1992. Bull. Sericult.
- Sbartai H., R. Rouabhi, I. Sbartai, H. Berrebbah and M.R. Djebar, 2007. Induction of anti-oxidative enzymes by cadmium stress in tomato (Lycopersiconesculentum) African J. Plant Sci., 2(8): 072-076.