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Daharwal, S. J.
- Plant Toxins: An Overview
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Affiliations
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, IN
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, IN
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Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 5 (2013), Pagination: 283-288Abstract
Toxins are naturally present in a wide variety of plants. Plants evolve to generate natural products as a means of defence against animals. Phytotoxins have been reported for many useful effects. Some plants produce toxins that can severely harm or destroy any herbivore. They can be modified to exemplify improved affinity and efficacy for health endorsement. Several of these plants are commonly consumed as food. They have been developed as an evolutionary movement for self-protection. These toxic substances when taken in considerable amount can be harmful to human health and cause problems. This review gives an outline on different plant toxins, their mechanism of action and different toxicological effects due to plant toxins.Keywords
Toxins, Secondary Metabolites, Phytotoxin, Natural Product
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- Treatment Strategies in Burn Wounds: An Overview
Abstract Views :257 |
PDF Views:0
Authors
Deependra Singh
1,
Mukesh K. Nag
1,
Satish Patel
1,
Madhulika Pradhan
1,
Shikha Shrivastava
1,
S. J. Daharwal
1,
Manju R. Singh
1
Affiliations
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, IN
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 6 (2013), Pagination: 341-352Abstract
Wound healing involves a regulated sequence of cellular activity. These activities provide the foundation for the mechanisms of wound repair. Successful wound care involves optimizing local and systemic conditions in combination with an ideal wound healing environment. The basic steps of wound management are prevention of wound contamination, debridement of dead and dying tissue, removal of debris and contaminants, provision of adequate wound drainage, promotion of a viable vascular bed and selection of an appropriate method of closure. A wide variety of preparations and remedies of non-organic, organic, biogenic, and phytogenic origin have been devised and used in the topical treatment of burns. Many different strategies have been developed to influence this wound environment to provide a pathogen-free, protected, and moist area for healing to occur. This review discusses the physiology, type and management of burn wounds and future directions for this field.References
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- A New Profile of Therapeutic Potential and Toxicities of Antineoplastic Drugs
Abstract Views :464 |
PDF Views:2
Authors
R. D. Dubey
1,
A. R. Ahmad
1,
S. Paroha
1,
P. K. Sahu
1,
S. Verma
1,
S. J. Daharwal
1,
S. L. N. Prasad Reddy
2,
M. S. Qureshi
3
Affiliations
1 Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, IN
2 Samskruti College of Pharmacy, Kondapur, Ghatkesar, RR Dist., Hyderabad, Andhra Pradesh, IN
3 Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Andhra Pradesh, IN
1 Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, IN
2 Samskruti College of Pharmacy, Kondapur, Ghatkesar, RR Dist., Hyderabad, Andhra Pradesh, IN
3 Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Andhra Pradesh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 6 (2010), Pagination: 370-375Abstract
Anticancer or antineoplastic drugs are used to treat malignancies. Drug therapy may be used alone or in combination with other treatments such as surgery or radiation therapy. The available anticancer drugs have distinct mechanisms of action which may vary in their effects on different types of normal and cancer cells. A single cure for cancer has proved elusive since there is not a single type of cancer but as many as 100 different types of cancer. In addition, there are very few demonstrable biochemical differences between cancerous cells and normal cells. For this reason the effectiveness of many anticancer drugs is limited by their toxicity to normal rapidly growing cells. A final problem is that cancerous cells which are initially suppressed by a specific drug may develop a resistance to that drug. For this reason cancer chemotherapy may consist of using several drugs in combination for varying lengths of time.Keywords
Antineoplastic, Malignancies, Therapy, Toxicity.References
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