Research Journal of Pharmacology and Pharmacodynamics

Shaik Asha Begum ¹, T. Vinay Kumar ¹, Shaik Abdul Rahaman ², S. Joshna Rani ³, Sreya Kosanam ¹, Y. Veena ¹

Affiliations
1 Department of Pharmacology and Pharmacy Practice, Nirmala College of Pharmacy, Atmakur, Mangalagiri, AP, 522503, IN
2 Princiapl and Professor, Nirmala College of Pharmacy, Atmakur, Mangalagiri, AP, 522503., IN
3 IPT, SPMVV, Tirupati, AP, 517501., IN

Abstract

Guillain-Baree syndrome also called guillain–Barré–Strohl syndrome, Landry's paralysis, post - infectious polyneuritis whichis a rare, at one or two cases per 100, 000 people every year, where auto-immune disorder in which a persons own immune system damaged the nerves, causing muscule weakness and sometimes paralysis. GBS can cause symptoms that last for a few weeks to several years. Most people recover fully, but some have permanent nerve damage. some people have died of GBS. Several things are known to tigger GBS. About twothirds of people with GBS had diarrhea or a respiratory illness several weeks before developing symptoms. Infection with campylobacter jejuni, which causes diarrhea, is one of the most common risk factors for GBS. People can develop GBS after some other infections, such as flu, cytomegalovirus, Epstein barr virus, and zika virus. Very rarely, people have developed GBS in the days or weeks after receiving certain vaccines. It can be caused by campylobacter infection that is diagnosed when a laboratory tests detect campylobacter bacteria in stool, body tissue, or fluids. The test could be a culture that isolates the bacteria or a rapid diagnostic test that detects genetic material of the bacteria. The major aim of this case report is to present a classic case of this condition, to highlight an awareness of differing treatment options, and to advocate referral to a given its physician potential severity. Treatment for GBS including antibiotics, drink extra fluids as long as diarrhea lasts, plasma exchange, immunoglobulin therapy2 .

Keywords

Immune response, nervous system, immunoglobulins, plasmapheresis, Miller Fisher syndrome.

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