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Updated Review on Orally Disintergarting Tablets:Advancement in Current Trends


Affiliations
1 P.E.S’s, Modern College of Pharmacy (For Ladies), Moshi, India
2 Emcure Pharmaceuticals, Pune, India
     

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There is an increasing demand for the easily administered dosage forms and oral routes of drug administration have wide acceptance upto 50-60% of total dosage forms. The oral fast dissolving systems are defined as oral drug delivery systems that dissolve or disintegrate within a few seconds to a few minutes of placement in the mouth and that do not require water to aid swallowing. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-disintegrating tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed orally disintegrating tablets, as they may take up to a minute to completely disintegrate. Oral delivery is currently receiving the highest standards. Achieving the highest standards in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. Fast- or mouth dissolving OR Orally disintegrating tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water.

Keywords

Mouth Dissolving Tablets, Superdisintegrants, Evaluation of Mouth Dissolving Tablets.
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  • Updated Review on Orally Disintergarting Tablets:Advancement in Current Trends

Abstract Views: 194  |  PDF Views: 0

Authors

Smita Kolhe
P.E.S’s, Modern College of Pharmacy (For Ladies), Moshi, India
Dhananjay More
Emcure Pharmaceuticals, Pune, India

Abstract


There is an increasing demand for the easily administered dosage forms and oral routes of drug administration have wide acceptance upto 50-60% of total dosage forms. The oral fast dissolving systems are defined as oral drug delivery systems that dissolve or disintegrate within a few seconds to a few minutes of placement in the mouth and that do not require water to aid swallowing. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-disintegrating tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed orally disintegrating tablets, as they may take up to a minute to completely disintegrate. Oral delivery is currently receiving the highest standards. Achieving the highest standards in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. Fast- or mouth dissolving OR Orally disintegrating tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water.

Keywords


Mouth Dissolving Tablets, Superdisintegrants, Evaluation of Mouth Dissolving Tablets.