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Experimental Study of Analgesic Activity of Cajanus cajan Linn Leaves in Mice


Affiliations
1 Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
2 Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
     

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Cajanus cajan L (fabaceae) is an important indigenous plant with a lot of traditional importance. The analgesic potency of aqueous extract of the leaves of Cajanus cajan L was investigated using animal model using writhing methods, formalin induced methods. Result showed that aq. extract of Cajanus cajan L increased pain threshold in mice using writhing methods, formalin induced methods. It is concluded that the aqueous extract of Cajanus cajan L can demonstrate strong analgesic potency comparable in a times and dose dependant manner to a non steroidal anti-inflammatory drugs. The result tends to suggest that the extracts of Cajanus cajan L leaves posses analgesic activity.

Keywords

Cajanus cajan L, Analgesic Activity, Writhing Methods, Formalin Induced Methods.
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  • Experimental Study of Analgesic Activity of Cajanus cajan Linn Leaves in Mice

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Authors

R. S. Ghodake
Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
U. S. Chikhali
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
A. D. Shinde
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
S. B. Patil
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India
N. S. Naikwade
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli 416416, India

Abstract


Cajanus cajan L (fabaceae) is an important indigenous plant with a lot of traditional importance. The analgesic potency of aqueous extract of the leaves of Cajanus cajan L was investigated using animal model using writhing methods, formalin induced methods. Result showed that aq. extract of Cajanus cajan L increased pain threshold in mice using writhing methods, formalin induced methods. It is concluded that the aqueous extract of Cajanus cajan L can demonstrate strong analgesic potency comparable in a times and dose dependant manner to a non steroidal anti-inflammatory drugs. The result tends to suggest that the extracts of Cajanus cajan L leaves posses analgesic activity.

Keywords


Cajanus cajan L, Analgesic Activity, Writhing Methods, Formalin Induced Methods.