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Potentiation of the Fungicidal Activity 1-(2, 4- Dihydroxyphenyl) Ethanone Ligand and Its Divalent Metal Complexes


Affiliations
1 Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
2 Department of Pharmacy, Nnamdi Azikiwe University, Awka, Nigeria
3 Department of Chemistry, Anambra State University, Uli, Nigeria
     

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Newly synthesized 1-(2, 4-Dihydroxyphenyl) Ethanone ligand and its Co(II), Ni(II), Zn(II) and Pd(II) metal complexes were tested for their fungicidal potentials against Gibberela, Cercospora arachidicola, Physolopora piricola and Fusarium oxysporium.

Preliminary in vitro test for fungicidal activity of the ligand and complexes were carried out by the fungi growth inhibition method. In general, the ligand and the complexes displayed certain activity against the fungi species at 25ppm, 50ppm and 100ppm. The complexes are more toxic to the fungi species than the uncomplexed ligand at different concentrations. The inhibition percentage of the ligand and complexes increases as the concentration increases. The metal complexes show more increased activity than the corresponding ligands.


Keywords

1-(2, 4-Dihydroxyphenyl) Ethanone, Fungi, Inhibition, Complexes.
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  • Potentiation of the Fungicidal Activity 1-(2, 4- Dihydroxyphenyl) Ethanone Ligand and Its Divalent Metal Complexes

Abstract Views: 228  |  PDF Views: 1

Authors

I. E. Otuokere
Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
G. U. Okafor
Department of Pharmacy, Nnamdi Azikiwe University, Awka, Nigeria
A. J. Chinweuba
Department of Chemistry, Anambra State University, Uli, Nigeria

Abstract


Newly synthesized 1-(2, 4-Dihydroxyphenyl) Ethanone ligand and its Co(II), Ni(II), Zn(II) and Pd(II) metal complexes were tested for their fungicidal potentials against Gibberela, Cercospora arachidicola, Physolopora piricola and Fusarium oxysporium.

Preliminary in vitro test for fungicidal activity of the ligand and complexes were carried out by the fungi growth inhibition method. In general, the ligand and the complexes displayed certain activity against the fungi species at 25ppm, 50ppm and 100ppm. The complexes are more toxic to the fungi species than the uncomplexed ligand at different concentrations. The inhibition percentage of the ligand and complexes increases as the concentration increases. The metal complexes show more increased activity than the corresponding ligands.


Keywords


1-(2, 4-Dihydroxyphenyl) Ethanone, Fungi, Inhibition, Complexes.