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Pharmacological Study and Phytochemical Study of Celastrus paniculatus Seed


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1 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, 413736, Maharashtra, India
     

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The Celastrus paniculatus wild belongs to family Celastraceae. In Ayurveda is known as ‘Tree of life’ and ‘Elixir of life’. It is commonly known as Malkangani and Jyothishmati in Hindi and Sanskrit respectively. The plant contains bioactive compound such as Alkaloids, Tannins, Flavonoids, Saponins, Steroids, Terpenoids, Phlobatannins, Cardiac Glycosides and Phenolic Compound. seed oil are the most used parts of this deciduous plant and oral and intranasal routes are most preferred for delivering this drug in Ayurveda. Different studies have show that it has various pharmacological activities which involve neuroprotective activity, rejuvenative activity, cardiovascular activity, analgesic activity, anti-inflammatory activity, anti-infertility activity, antioxidant activity, free radical scavenging activity anti-arthritic activity etc. Mainly oil from seeds is used for stimulating intellect, sharpening memory and in the treatment of brain related disorder of all the age category. It also reported as a potential nervine tonic, rejuvenator and an anti-depressant. Celastrus paniculatus Willd is one of the medicinal plant having its importance in health care system as a indegenous medicinal plant also. The seed involve steroid alkaloids and bright natural coloring matter, celapanine, celapanigine, celapagine, celastrine, and paniculatine are the important alkaloids.

Keywords

Malkangani, Celapanine, Abortifacient, Flavonoid, Jyotishmati.
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  • Kamalinee Deodhar A, Nanda Shinde W. Celastrus paniculatus; medicinal and pharmacological properties: A Review, International journal of development research 2015; 5(9): 5526-5531.
  • Kanti Rekha, Bhan MK, Balyan SS, Dhar AK. Cultivation prospects of endangered species Celastrus paniculatus wild, Natural product radiance (green page article) 2005; 4(6): 482-486.
  • Sharma P, Dravyaguna vijnana. Chaukhambha Bharati Academy, Varanasi, 2018.
  • Monojit D, Pushpan R, Harshita K and War N, Medico ethnobotanical perspectives of jyotismati (Celastrus paniculatus) Willd): A herbal tranquilizer, Journal of Drug Delivery and Therapeutics 2, 2012, 8-11.
  • Sharma GN, Kaur H, Shrivastava B, Arora SC, A review from historical to current Celastrus paniculatus, International Journal of Pharmacy and Pharmaceutical Sciences, 2020, 12(8):15-20.
  • Deodhar KA, Shinde NW. Celastrus paniculatus Traditional uses and Ethnobotanical study. Ind J of Adv in Plant Research 2015; 2(1):18-21
  • Parimala S, Shashidhar GH, Ch. Sridevi, Jyothi V, Suthakaran R, Anti- inflammatory activity of Celastrus paniculatus seeds, International Journal of Pharm Tech Research, 2009; 1(4):1326- 1329.
  • Ahmad F, Khan R A, Rasheed S, Preliminary screening of methanolic Extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti- inflammatory activities, Journal of Ethnopharmacology, 1994; 42(3):193-198, ISSN 0378-8741.
  • Vijay R, Shukla J, Saxena R. In vitro Effect of Various Plant Growth Regulator on Micro Propagation of Celastrus paniculatus: An Important Medicinal Plant. International Journal of Current Microbiology and Applied Sciences 2016; 5(12): 635-643.
  • Avinish DK,Waman S Nanda. Phytochemical Constituents of Leaves of Celastrus paniculatus Wild: Endangered Medicinal Plant. Inter J Pharmacog and Phytochem Research 2014; 6(4): 792-794. 24.
  • Venkataramaiah CH, Rajendra Wudayagiri. Phytochemical Screening of Bioactive Compounds Present in the Seed of Celastrus paniculatus Role in Traditional Medicine. Seasons. Indo Ameri J of Pharm Research 2013; 3(11): 9104-9111.
  • Sumathi TC, Shobana V, Mahalakshmi R, Sureka M, Subathra A, Vishali, et al. Oxidative stress in the brains of male rats intoxicated with aluminium and neuromodulating effect of Celastrus paniculatus alcoholic seed extract. Asian J Pharm Clin Res 2013; 6:80-90.
  • Nakhva YJ, Anandpara RC, Sojitra BN, Ganatra TH. Evaluation of iron-chelating potential of methanolic extract of seeds of Celastrus paniculatus on iron intoxicated rats. J Chem Pharm Res 2015; 12:1104-12.
  • Kothavade PS, Bulani VD, Deshpande PS, Chowdhury AS, Juvekar AR. The petroleum ether fraction of Celastrus paniculatus Wild. seeds demonstrate the anti-arthritic effect in adjuvant-induced arthritis in rats. J Trad Chin Med Sci 2015; 2:183-93.
  • Thangaraj P. In vitro anti-arthritic activity, pharmacological assays of plant-based natural products, Progress in Drug Research, Springer, Cham; 2016. p. 71.
  • Athira Sajeev CR, Saroj KR, Sooraj NP, Sunil Kumar KN, Jaishanker R. Mapping traditional knowledge associated with Celastrus paniculatus in India using geographical information system (GIS), journal of Ayurveda medical science 2016; 1(2) :55 -62.

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  • Pharmacological Study and Phytochemical Study of Celastrus paniculatus Seed

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Authors

Tejashri S. Shinde
Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, 413736, Maharashtra, India
Ravindra S. Jadhav
Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, 413736, Maharashtra, India
Dattaprasad N. Vikhe
Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, 413736, Maharashtra, India

Abstract


The Celastrus paniculatus wild belongs to family Celastraceae. In Ayurveda is known as ‘Tree of life’ and ‘Elixir of life’. It is commonly known as Malkangani and Jyothishmati in Hindi and Sanskrit respectively. The plant contains bioactive compound such as Alkaloids, Tannins, Flavonoids, Saponins, Steroids, Terpenoids, Phlobatannins, Cardiac Glycosides and Phenolic Compound. seed oil are the most used parts of this deciduous plant and oral and intranasal routes are most preferred for delivering this drug in Ayurveda. Different studies have show that it has various pharmacological activities which involve neuroprotective activity, rejuvenative activity, cardiovascular activity, analgesic activity, anti-inflammatory activity, anti-infertility activity, antioxidant activity, free radical scavenging activity anti-arthritic activity etc. Mainly oil from seeds is used for stimulating intellect, sharpening memory and in the treatment of brain related disorder of all the age category. It also reported as a potential nervine tonic, rejuvenator and an anti-depressant. Celastrus paniculatus Willd is one of the medicinal plant having its importance in health care system as a indegenous medicinal plant also. The seed involve steroid alkaloids and bright natural coloring matter, celapanine, celapanigine, celapagine, celastrine, and paniculatine are the important alkaloids.

Keywords


Malkangani, Celapanine, Abortifacient, Flavonoid, Jyotishmati.

References