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Magdum, C. S.
- Formulation and Optimization of Dermatological Dosage form for Comparative in-vitro Evaluation of Semisolid Bases
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Authors
Affiliations
1 Rajarambapu College of Pharmacy, Kasegaon, Tal- Walwa, Dist-Sangli, IN
1 Rajarambapu College of Pharmacy, Kasegaon, Tal- Walwa, Dist-Sangli, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 7, No 2 (2016), Pagination: 46-54Abstract
The aim of this study was to improve the permeation of Diclofenac Sodium. Permeation studies were carried out in - vitro using cellophane membrane. Topical formulations of diclofenac sodium were prepared by using various polymers. Gel, cream and ointment of the drug were prepared with polymers and the formulations were subjected for evaluation. Gel formulations were containing carbopol 940, triethanolamine, and preservatives. Cream was formulated by using stearic acid, glycerin, lanolin and preservatives. Ointment was also formulated by using the ingredients cetostearyl alcohol, hard paraffin, white soft paraffin and wool fat. In-vitro permeation studies by using cellophane membrane in diffusion cell revealed better permeation characteristics of diclofenac sodium. These types of topical dosage forms could give sustained delivery of drug on to the skin, so they are interesting promises to improve skin absorption of non steroidal anti-inflammatory drugs and to prevent side effects associated. The Topical formulations are excellent in the percutaneous absorption of diclofenac or its salts and provide good properties upon use and superior medical effects of diclofenac or its salts.Keywords
Diclofenac Sodium, Gel, Cream, Ointment, Diffusion Cell.- Formulation of Gel and its UV Protective Study of Some Medicinal Flowers
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Authors
Affiliations
1 Appasaheb Birnale College of Pharmacy, South Shivajinagar, Sangli – 416416, IN
2 Rajarambapu College of pharmacy, Kasegaon, Sangli, IN
1 Appasaheb Birnale College of Pharmacy, South Shivajinagar, Sangli – 416416, IN
2 Rajarambapu College of pharmacy, Kasegaon, Sangli, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 2, No 2 (2011), Pagination: 64-65Abstract
The present study was designed to prepare sunscreen herbal formulations gel. Hibiscus rosa-sinesis L. (Malvaceae), Rosa Damascena (Rosaceae), Spathodea campanulata L. (Bignoniaceae) is one of the well-known drugs for its therapeutic values in traditional medicine. In the present study the drug was screened for its cosmetic use. All the three herbal drugs containing flavonoid showed sunscreen activity. The sunscreen activities of gel formulations could be related to the free radical scavenging properties of polyphenol compounds in the extracts incorporated in it. The method is performed by UV -visible spectrophotometry in the range of 200-400nm. Result of the extracts alone and gel formulation showed maximum absorbance at 270-300nm.Keywords
Hibiscus rosa-sinesis L,Rosa damascena, Spathodea campanulata L. Sunscreen Gel.- Formulation and Evaluation of Polyherbal Anti-Acne Gel
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Authors
A. C. Patil
1,
A. R. Patil
1,
A. C. Patil
1,
S. J. Shid
1,
V. N. Dange
1,
C. S. Magdum
1,
S. K. Mohite
1
Affiliations
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 8, No 2 (2017), Pagination: 61-63Abstract
Acne is an infection of the skin, caused by changes in the sebaceous glands. The most common form of acne is called acne vulgaris, which means "common acne". The redness comes from the inflammation of the skin in response to the infection. One of the most common disorders found among youngsters usually 18-25 years of age is Acne. Acne vulgaris, which is a skin disorder of the pilosebaceous gland leads to the formation of inflammatory lesions, seborrhea etc. There is a remarkable demand of herbal formulations in the global market. Acne is a popular disorder among the teenagers which make them feel unappealing to look at and also a sort of inferior feel. They take many measures to avoid and cure acne. Plants are well known for their medicinal and cosmetic uses.Keywords
Acne, Neem, Nutmeg.References
- Vijayalakshmi A, Tripura A, Ravichandiran V. Development and evaluation of anti acne products from Terminalia arjuna Bark. Int J Pharmtech Research. 3(1) (2011)320-327.
- Goulden Victoria. Guidelines for the management of acne vulgaris in adolescents. Pediatr. Drugs. 5(2003): 301-313.
- Gopal M.G, Farahana B, Dr. Kala Suhas Kulkarni, Effectiveness of Herbal Medication in treatment of Acne vulgaris- A pilot Study, The Indian Practioner; 2001, 54, 10, 723.
- R. S. Adnaik, D. A. Bhagwat, I. D. Raut, S. K. Mohite, C. S. Magdum, Laxative and Anthelmintic potential of cassia alata flower extract, Research Journal of Pharmacy and Technology. Vol-04, No.01, January 2011, 98-100.
- Kanlayavattanakul. M., Lourith N. Therapeutic agents and herbs in topical application for acne treatment. Int. J. Cosmetic Sci. 2011; 33:289-29.