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Manogna, Katta.
- Polymeric Novel Vesicular Drug Delivery System:An Updated Overview of Microspheres
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1 S V U College of Pharmaceutical Sciences, S V University, Tirupati, IN
1 S V U College of Pharmaceutical Sciences, S V University, Tirupati, IN
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Research Journal of Topical and Cosmetic Sciences, Vol 8, No 2 (2017), Pagination: 64-71Abstract
Microspheres are categorized under the vesicular drug delivery system, encapsulated by proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. The internal structure of the microspheres can vary as a function of the microencapsulation process employed. The encapsulation is carried out by various preparation methods. Microspheres are multiparticulate drug delivery systems which are prepared to obtain prolonged or controlled drug delivery to improve bioavailability, stability and to target the drug to specific site at a predetermined rate. Drugs can be targeted to specific sites in the body using microspheres. The rate of drug release from the microspheres dictates their therapeutic action. Release is governed by the molecular structure of the drug and the polymer, the resistance of the polymer to degradation, and the surface area along with the porosity of the microspheres. This article aims to provide a comprehensive review of advantages, methods of preparation, mechanism, routes of administration, different types of microspheres based on natural and synthetic biodegradable polymers and application of biodegradable polymeric microspheres.Keywords
Microspheres, Microencapsulation, Polymers, Controlled Drug Delivery, Biodegradable.References
- Rashmi MS. Topical Gel: A Review, Available, from; http://www.pharmainfo.net/review/topical-gel-review 2008.
- B Amsden. The production of uniformity sized polymer microspheres. Pharm. Res., 1999a 16(7): 1140-1143
- Chaturvedi G and Saha RN. A review on microsphere technology and its applications. Birla Institute of Technology and Sciences. 2009:56-58.
- V. Sankar, S. Ramesh, V. Shanmugam. A Text Book of Novel Drug Delivery Systems: Pharma Med Press, 2012, 49-60.
- Kavita kunchu, Raje Veera Ashwani et al. Albumin microspheres: a unique system as drug delivery carriers for non steroidal Anti Inflammatory Drugs. 2010; 5(2):12
- Sudha Mani T and Naveen Kumar K. At preparation and evaluation of ethyl cellulose microspheres of ibuprofen for sustained drug delivery. International Journal of Pharma Research and Development. 2010;2(8):120-121.
- Kreuter J., Nefzger M., LIehl E., Czokr. And Voges R. 1983 J. Pharma Sci.72, 1146.
- Wakiyama N., Juni K. and Nakano m.1981 chem. Pharm.Bull.29, 3363.
- Sugibayashi K, Akimoto M., Moromoto Y., Nadai T. and Kato Y. 1979 Pharmacobiodyn 23,50.
- Chitra Singh, Suresh Purohit, Madhu Singh, B. Pandey design and evaluation of microspheres: a review. Journal of Drug Delivery Research. ISSN: 2319-1074.
- Alagasundaram M., Madhu Sudana Chetty. C, Umashankari. K, microspheres as a novel drug delivery system - a review. International Journal of Chemtech research. July Sept 2009 ISSN: 0974-4290 vol. 1, no.3, pp 526-534.
- Sahil, Middha Akansa, Sandhu Premjeet, Ajay Bilandi and Bhawana Kapoor Seth G.L. Bihani S.D. microspheres a review: technical education, institution of pharmaceutical sciences and drug research, aspects of International Journal of Research in Pharmacy and Chemistry, IJRPC 2011,ISSN: 2231-2781.
- Tamizhrasi S,Shukala.A, Shivkumar T, Rathi V, Rathi JC. Formuation and evaluation of lamivusdine loaded poly methacrylic acid nanoparticles. International Journal of Pharm Tech Research,2009:1:411-415.
- Shiv Shankar Hardenia, Ankit Jain, Ritesh Patel, Anu Kaushal, formulation and evaluation of mucoadhesive microspheres of ciprofloxacin. Journal of Advanced Pharmacy Education & Research 1(4):214-224(2011)ISSN 2249-3379.