Antibacterial Susceptibility and Virulence Factors of Klebsiella Species Isolated from Urinary Tract Infections in Coimbatore, South India

Klebisella species are reported more frequently as the common causative agent of urinary tract infections (UTI) around the world. Thirty species of Klebsiella isolates from patients with UTI were subjected for the investigation of virulence factors and the antibiotic susceptibility pattern. Antibiotics susceptibility by disk diffusion revealed that all the isolates were sensitive to imipenem 100% (n=30). Minimum Inhibitory Concentration (MIC) analysis against tetracycline revealed that out of 30 isolates, all the isolates (n=30) had the MIC value of 16μg/mL. The MIC values for gentamycin were 8 and 4μg/mL for 29 isolates and one isolate had MIC value at 4μg/mL. The MBC values for tetracycline were 64μg/mL for majority of the isolates (n=29), whereas K11 showed the highest value of 128μg/mL. A total of 8 isolates showed slime production and these isolates were analyzed for biofilm formation and hemolysis. It was noted that Klebsiella played a very dominant role in causing urinary tract infections.