SMU Medical Journal

Open Access Open Access  Restricted Access Subscription Access

Isolation and Characterization of a Compound from the Leaves of Amaranthus spinosus Linn.


Affiliations
1 Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India
2 Department of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
3 Department of Biochemistry, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
4 Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430, Siliguri, West Bengal, India
 

By solvent extraction, acid hydrolysis, chromatography followed by crystallization, a compound was isolated from the leaves of Amaranthus spinosus Linn. Infra red spectroscopy, mass spectroscopy and nuclear magnetic resonance studies showed that the isolated compound was chemically 3,4 dihydroxy benzoic acid.

Keywords

Amaranthus spinosus Linn., Chromatographic Techniques, 3,4 Dihydroxy Benzoic Acid.
User
Notifications
Font Size

  • Chopra Col Sir RN and Chopra IC. (1958) Indigenous drugs of India, U.N.Dhar and Sons Private Limted, Kolkata, P. 605

  • Das AP and Ghosh Chandra.(2009) Germplasm collection in garden of medicinal plants. University of North Bengal, Siliguri, West Bengal, P. 8.

  • Kirtikar KR and Basu BD. (2001) Indian Medicinal Plants, vol. 9, 2nd ed.Oriental Enterprises, Rajpur, Dehradun, Uttaranchal, India, p. 2832-2836

  • Hussain Zeashan, Amresh G, Singh Satyawan and Rao Chandana Venkateswara. (2009) Anti diarrheal and anti ulcer effect of Amaranthus spinosus Linn. Pharmaceutical Biology, 47, 932– 39.

  • Olufemi BE, Assiak IE, Ayoade GO and Onigemo MA. (2003) Studies on the effects of Amaranthus spinosus leaf extract on the hematology of growing pigs. Afr J Biomed Res. 6, 149-150.

  • Tatiya AU, Surana SJ, Khope SD, Gokhale SB and Sutar MP.(2007) Phytochemical investigation and immunomodulatory activity of Amaranthus spinosus Linn. Indian J Pharm Edu Res 44, 337 – 341.

  • Assiak IE, Olufemi BE, Ayonde GO and Onigemo MA. (2002) Preliminary studies on the effects of Amaranthus spinosus leaf extract as an Anthelmintic in growing pigs. Trop Vet ; 20,126-129.

  • Sangameswaran B and Jayakar B. (2008) Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats. J Nat Med 62, 79-82.

  • Girija K and Lakshman K. (2011) Anti-hyperlipidemic activity of methanol extracts of three plants of Amaranthus in triton-WR 1339 induced hyperlipidemic rats. Asian Pac J Trop Biomed 1, s62-s65

  • Gurung Bejoy. (2002) The medicinal plants of Sikkim Himalaya. Pub. Bejoy Gurung, East Sikkim. P. 55.

  • Ghosh Debiprasad, Mitra Prasenjit, Ghosh Tanaya, Salhan Ravindernath, Singh Takhelmayum Amumachi, Chakrabarti Amit and Mitra Prasanta Kumar.(2013) Role of Amaranthus spinosus Linn. in experimental peptic ulcer. Bioscience Guardian. 3(1), 13-18.

  • Odhava B, Beekrumb S, Akulaa U and Baijnath H.(2007) Preliminary assessment of nutritional value of traditional leafy vegetables in KwaZulu-Natal, South Africa. J Food Compos Anal, 20,430-435.

  • Barminas T, Charles M and Emmanuel D.(1998) Mineral composition of nonconventional leafy vegetables. Plant Foods Hum Nutri, 53, 29-36.


Abstract Views: 381

PDF Views: 99




  • Isolation and Characterization of a Compound from the Leaves of Amaranthus spinosus Linn.

Abstract Views: 381  |  PDF Views: 99

Authors

Prasanta Kumar Mitra
Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India
Tanaya Ghosh
Department of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
Prasenjit Mitra
Department of Biochemistry, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
Sumanta Gupta
Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430, Siliguri, West Bengal, India
Basudeb Basu
Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430, Siliguri, West Bengal, India

Abstract


By solvent extraction, acid hydrolysis, chromatography followed by crystallization, a compound was isolated from the leaves of Amaranthus spinosus Linn. Infra red spectroscopy, mass spectroscopy and nuclear magnetic resonance studies showed that the isolated compound was chemically 3,4 dihydroxy benzoic acid.

Keywords


Amaranthus spinosus Linn., Chromatographic Techniques, 3,4 Dihydroxy Benzoic Acid.

References