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Chandrasekaran, Natarajan
- Optimization of Process Parameters to Develop Nanoemulsion by Ultrasound Cavitation
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Authors
Affiliations
1 Centre for Nanobiotechnology, VIT University, Vellore-632014, Tamil Nadu, IN
1 Centre for Nanobiotechnology, VIT University, Vellore-632014, Tamil Nadu, IN
Source
Journal of Pure and Applied Ultrasonics, Vol 37, No 2-3 (2015), Pagination: 53-56Abstract
Nanoemulsions are colloidal dispersions of oil and water stabilized by interfacial layer of surfactant with droplet size ranging between 20 nm and 200 nm. The reduced droplet size makes the system optically transparent/translucent due to weak scattering of light waves. Also the very low droplet size of the nanoemulsion improves the stability of the system when compared to emulsion with greater droplet size. In the present study, plant essential oil based oil-in-water nanoemulsion was formulated by ultrasound cavitation method which was stabilized by interfacial layer of non-ionic surfactant. Development of oil-in-water nanoemulsion was optimized for different process parameters such as surfactant type, surfactant concentration and emulsification times to obtain nanoemulsion with lower droplet size and greater stability.Keywords
Ultrasound Cavitation, Nanoemulsion, Plant Essential Oil, Tween 20, Tween 80.Full Text
- Ultrasonic Emulsification:Reduces Droplet Diameter and Enhances Stability
Abstract Views :179 |
PDF Views:0
Authors
Affiliations
1 Centre for Nanobiotechnology, VIT University, Vellore-632014, Tamil Nadu, IN
1 Centre for Nanobiotechnology, VIT University, Vellore-632014, Tamil Nadu, IN
Source
Journal of Pure and Applied Ultrasonics, Vol 36, No 1 (2014), Pagination: 13-16Abstract
Nanoemulsions are colloidal dispersions of two immiscible liquids (oil and water) with droplet sizes between 20 and 200 nm. The efficient production of nanoemulsions with very low oil droplet sizes facilitates the inclusion of oil soluble bioactive substances into a range of water based foods and also in delivery of lipophilic drugs. Stability of nanoemulsion is one of the major concerns when we consider its applications. With exception to few (as in spontaneous emulsification), energy input is required to formulate nanoemulsion. In this present study, we assessed the effect of ultrasound on stability and droplet size of emulsion. The nanoemulsion formulated by emulsification time of 2 min, 5 min, 10 min and 15 min demonstrated stability for 1 day, 10 days, 30 days and 60 days respectively. Also we studied the performance of ultrasound emulsification with that of classical mechanical agitation. Coarse emulsion prepared by classical mechanical agitation, without being subjected for ultrasonic emulsification) exhibited phase separation within 2 hrs of preparation. Hence we conclude that emulsification time had a direct relation with the stability of nanoemulsion, which was due to the size reduction by ultrasound.Keywords
Basil Oil, Nanoemulsion, Stability, Ultrasonic Emulsification, Emulsification Time.Full Text