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Epidemiological Aspects of Cutaneous Leishmaniasis in Southwest of Iran


Affiliations
1 Health Center of Tangestan, Bushehr University of Medical Sciences, Bushehr, Iran, Islamic Republic of
2 Department of Public Health, Qom University of Medical Sciences, Qom, Iran, Islamic Republic of
3 Department of Public Health, School of Public Health, Ardabil University of Medical Science, Ardabil, Iran, Islamic Republic of
4 Isfahan Health Research Station, National Institute of Health Research, Tehran University of Medical Sciences, Tehran,, Iran, Islamic Republic of
5 Department of Microbiology and Immunology, Qom University of Medical Sciences, Qom, Iran, Islamic Republic of
6 The Persian Gulf Tropical Medicine Research Center, the Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran, Islamic Republic of
 

Background and Aim: Zoonotic rodents (Rodentia: Muridae: Gerbillinae) and Phlebotominae sand flies are the major reservoir hosts and vectors of Leishmania major causing zoonotic cutaneous leishmaniasis, respectively. This study was carried out to evaluate the epidemiological aspects of cutaneous leishmaniasis (CL) in Tangestan County, Southwest Iran.

Materials and Methods: This descriptive cross-sectional study was carried out on human cases, probable reservoirs, and vectors of CL at Tangestan County in 2017. The data of patients were taken on health centers and analyzed. To determination faunistic of sand flies, they were collected using sticky paper traps and identified using identification keys. The rodent samples were captured using Sherman live traps and determined for amastigote infection.

Results: A total of 436 cases occurred during 2005-2017 and the incidence rate of disease was 0.2-12/100,000 people. Six species of sand flies including three species of Phlebotomus and three species of Sergentomyia including Phlebotomus papatasi, Phlebotomus sergenti, Phlebotomus alexandri, Sergentomyia tiberiadis, Sergentomyia baghdadis, and Sergentomyia clydei were identified. From 185 trapped rodents, 9 species were identified. We founded, 2 out of 132 Tatera indica (1.53%) were positive with Leishmania spp. using the microscopic method.

Conclusion: According to the existence of human leishmaniasis cases as a host, T. indica with high abundance and infected to Leishmania as a reservoir, and existence of P. papatasi with high abundance as a suspected vector of disease; there is a potential for transmission of disease in the area. Design of exact control and prevention strategies is highly recommended.


Keywords

Cutaneous Leishmaniasis, Iran, Rodents, Sand Flies.
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  • Yaghoobi-Ershadi MR, Akhavan AA, Zahraei-Ramazani AV, Abai MR, Ebrahimi B, Vafaei-Nezhad R, et al. Epidemiological study in a new focus of cutaneous leishmaniasis in the Islamic Republic of Iran. East Mediterr Health J 2003; 9:816-26.
  • Mohebali M, Hajjaran H, Hamzavi Y, Mobedi I, Arshi S, Zarei Z, et al. Epidemiological aspects of canine visceral leishmaniosis in the Islamic Republic of Iran. Vet Parasitol 2005; 129:243-51.
  • Norouzinezhad F, Ghaffari F, Norouzinejad A, Kaveh F, Gouya MM. Cutaneous leishmaniasis in Iran: Results from an epidemiological study in urban and rural provinces. Asian Pac J Trop Biomed 2016;6:614-9.
  • Piroozi B, Moradi G, Alinia C, Mohamadi P, Gouya MM, Nabavi M. Incidence, burden, and trend of cutaneous leishmaniasis over four decades in Iran. Iran J Public Health 2019; 48:28-35.
  • Rabiee MH, Mahmoudi A, Siahsarvie R, Kryštufek B, Mostafavi E. Rodent-borne diseases and their public health importance in Iran. PLoS Negl Trop Dis 2018;12: e0006256.
  • Akhoundi M, Mohebali M, Asadi M, Mahmodi MR, Amraei K, Mirzaei A, et al. Molecular characterization of Leishmania spp. In reservoir hosts in endemic foci of zoonotic cutaneous leishmaniasis in Iran. Folia Parasitol (Praha) 2013; 60:218-24.
  • Mohammadi S, Vazirianzadeh B, Fotouhi-Ardakani R, Novin EA, Amirkhani A. Tatera indica (Rodentia: Muridae) as the prior concern and the main reservoir host of zoonotic cutaneous leishmaniasis on the border of Iran and Iraq. Jundishapur J Microbiol 2017;10: e42452.
  • Theodor O, Mesghali A. On the phlebotominae of Iran. J Med Entomol 1964; 1:285-300.
  • Seyedi-Rashti MA, Nadim A. The genus Phlebotomus (Diptera: Psychodidae: Phlebotominae) of the countries of the Eastern Mediterranean region. Iran J Public Health 1992; 21:11-50.
  • Nikouee F, Soltanian M, Babaee F, Motamed-Jahromi M. Cutaneous leishmaniasis: An epidemiological survey in Iran during 2013-2015. J Nurs Midwifery Sci 2017; 4:58-62.
  • Saghafipour A, Vatandoost H, Zahraei-Ramazani AR, Yaghoobi-Ershadi MR, Jooshin MK, Rassi Y, et al. Epidemiological study on cutaneous leishmaniasis in an endemic area, of Qom Province, Central Iran. J Arthropod Borne Dis 2017; 11:403-13.
  • Tedla DG, Bariagabr FH, Abreha HH. Incidence and trends of leishmaniasis and its risk factors in Humera, Western Tigray. J Parasitol Res 2018; 2018:8463097.
  • Salimi M, Jesri N, Javanbakht M, Farahani LZ, Shirzadi MR, Saghafipour A, et al. Spatio-temporal distribution analysis of zoonotic cutaneous leishmaniasis in Qom Province, Iran. J Parasit Dis 2018; 42:570-6.
  • Traoré B, Oliveira F, Faye O, Dicko A, Coulibaly CA, Sissoko IM, et al. Prevalence of cutaneous leishmaniasis in districts of high and low endemicity in Mali. PLoS Negl Trop Dis 2016;10: e0005141.
  • Nateghi Rostami M, Saghafipour A, Vesali E. A newly emerged cutaneous leishmaniasis focus in Central Iran. Int J Infect Dis 2013;17: e1198-206.
  • Gholamrezaei M, Mohebali M, Hanafi-Bojd AA, Sedaghat MM, Shirzadi MR. Ecological niche modeling of main reservoir hosts of zoonotic cutaneous leishmaniasis in Iran. Acta Trop 2016; 160:44-52.
  • Kassiri H, Javadian E, Abdigoudarzi M. Natural Leishmania infection in Meriones hurrianae and Tatera indica (Rodentia: Cricetidae: Gerbillinae) in Sistan-Baluchistan Province, South Eastern of Iran. Adv Stud Biol 2011; 3:247-56.
  • Esfandiari B, Nahrevanian H, Pourshafie MR, Gouya MM, Khaki P, Mostafavi E, et al. Epidemiological distribution of rodents as potent reservoirs for infectious diseases in the provinces of Mazandaran, Gilan and Golestan, Northern Iran. Infect Dis Rep 2017; 9:6900.
  • Yaghoobi-Ershadi M. Phlebotomine sand flies (Diptera: Psychodidae) in Iran and their role on Leishmania transmission. J Arthropod Borne Dis 2012; 6:1-7.
  • Saghafipour A, Vatandoost H, Zahraei-Ramazani AR, Yaghoobi-Ershadi MR, Rassi Y, Shirzadi MR, et al. Spatial distribution of phlebotomine sand fly species (Diptera: Psychodidae) in Qom Province, Central Iran. J Med Entomol 2017; 54:35-43.

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  • Epidemiological Aspects of Cutaneous Leishmaniasis in Southwest of Iran

Abstract Views: 358  |  PDF Views: 91

Authors

Mohammad Darvishi
Health Center of Tangestan, Bushehr University of Medical Sciences, Bushehr, Iran, Islamic Republic of
Abedin Saghafipour
Department of Public Health, Qom University of Medical Sciences, Qom, Iran, Islamic Republic of
Eslam Moradi-Asl
Department of Public Health, School of Public Health, Ardabil University of Medical Science, Ardabil, Iran, Islamic Republic of
Reza Jafari
Isfahan Health Research Station, National Institute of Health Research, Tehran University of Medical Sciences, Tehran,, Iran, Islamic Republic of
Seyed Jafar Adnani Sadati
Department of Microbiology and Immunology, Qom University of Medical Sciences, Qom, Iran, Islamic Republic of
Hossein Darabi
The Persian Gulf Tropical Medicine Research Center, the Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran, Islamic Republic of

Abstract


Background and Aim: Zoonotic rodents (Rodentia: Muridae: Gerbillinae) and Phlebotominae sand flies are the major reservoir hosts and vectors of Leishmania major causing zoonotic cutaneous leishmaniasis, respectively. This study was carried out to evaluate the epidemiological aspects of cutaneous leishmaniasis (CL) in Tangestan County, Southwest Iran.

Materials and Methods: This descriptive cross-sectional study was carried out on human cases, probable reservoirs, and vectors of CL at Tangestan County in 2017. The data of patients were taken on health centers and analyzed. To determination faunistic of sand flies, they were collected using sticky paper traps and identified using identification keys. The rodent samples were captured using Sherman live traps and determined for amastigote infection.

Results: A total of 436 cases occurred during 2005-2017 and the incidence rate of disease was 0.2-12/100,000 people. Six species of sand flies including three species of Phlebotomus and three species of Sergentomyia including Phlebotomus papatasi, Phlebotomus sergenti, Phlebotomus alexandri, Sergentomyia tiberiadis, Sergentomyia baghdadis, and Sergentomyia clydei were identified. From 185 trapped rodents, 9 species were identified. We founded, 2 out of 132 Tatera indica (1.53%) were positive with Leishmania spp. using the microscopic method.

Conclusion: According to the existence of human leishmaniasis cases as a host, T. indica with high abundance and infected to Leishmania as a reservoir, and existence of P. papatasi with high abundance as a suspected vector of disease; there is a potential for transmission of disease in the area. Design of exact control and prevention strategies is highly recommended.


Keywords


Cutaneous Leishmaniasis, Iran, Rodents, Sand Flies.

References