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Stability Indicating Assay Method by UV Spectrophotometry for Estimation of Ofloxacin and Flavoxate Hydrochloride in Tablet Dosage Form


Affiliations
1 P. E. Society's, Modern College of Pharmacy, Nigdi, Pune – 411044, India
 

The present research work discusses the development of a stability-indicating UV spectrophotometric method for the estimation of Ofloxacin and Flavoxate hydrochloride in tablet dosage form. The optimum conditions for the analysis of the drug were established. The maximum wavelength (λmax) was found to be 266 nm for ofloxacin and 272 nm for flavoxate. Degradation studies of ofloxacin and flavoxate showed prominent degradation in acid hydrolysis.

Keywords

Stability Indicating, Ofloxacin, Flavoxate, UV Spectrophotometry.
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  • Stability Indicating Assay Method by UV Spectrophotometry for Estimation of Ofloxacin and Flavoxate Hydrochloride in Tablet Dosage Form

Abstract Views: 130  |  PDF Views: 85

Authors

Mahendra Rathod
P. E. Society's, Modern College of Pharmacy, Nigdi, Pune – 411044, India
Shailaja B. Jadhav
P. E. Society's, Modern College of Pharmacy, Nigdi, Pune – 411044, India
Priyanka Satpute
P. E. Society's, Modern College of Pharmacy, Nigdi, Pune – 411044, India
Prasanna Pisal
P. E. Society's, Modern College of Pharmacy, Nigdi, Pune – 411044, India

Abstract


The present research work discusses the development of a stability-indicating UV spectrophotometric method for the estimation of Ofloxacin and Flavoxate hydrochloride in tablet dosage form. The optimum conditions for the analysis of the drug were established. The maximum wavelength (λmax) was found to be 266 nm for ofloxacin and 272 nm for flavoxate. Degradation studies of ofloxacin and flavoxate showed prominent degradation in acid hydrolysis.

Keywords


Stability Indicating, Ofloxacin, Flavoxate, UV Spectrophotometry.

References