Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Iniencephaly: A Case Report


Affiliations
1 Department of Pathology, Kasturba Medical College, Manipal University, Mangalore, India
     

   Subscribe/Renew Journal


Iniencephaly is an unusual malformation of variable incidence with involvement of the occiput (inion) and the brain. The features are: (1) Imperfect formation of the base of skull; (2) Rachischisis; (3) Retroflexion of the spine. We present a case report that illustrates the morphological features of iniencephaly. A multipara with 22 weeks gestation and history of gestational diabetes had a twin gestation with intrauterine death of both fetuses detected by ultrasound. An autopsy performed revealed one twin had features of iniencephaly while the other was morphologically normal. Iniencephaly is incompatible with life and its etiology is unknown requiring further experimental studies.

Keywords

Iniencephaly, Intrauterine Death
Subscription Login to verify subscription
User
Notifications
Font Size


  • Nishimura H, Chapter 10, Iniencephaly, Congenital malformations of the brain and skull, Volume 30, Vinken P.J, Bruyn G.W, Amsterdam, North-Holland publishing company, 1977, 257-268.
  • Aytar M H, Dogulu F, Cemil B, Ergun E, Kurt G, Baykaner K. Iniencephaly and long term survival: A rare case report. Childs Nervs Syst.2007;23: 719-721.
  • Myrianthopoulos N.C, Chapter 5, Epidemiology of central nervous system malformations, Congenital malformations of the brain and skull, Volume 30, Vinken P.J, Bruyn G.W, Amsterdam, North-Holland publishing company, 1977, 135-165.
  • Wigglesworth J.S, Chapter 14, The Central Nervous System, Perinatal Pathology, 2nd edition, Wigglesworth J.S, USA, W.B. Saunders Company, 1996, 222-235.
  • Ramakrishnan S, Sharma D, Ramakrishnan V, Parihar PS, Sharma S, Kanther DK. Iniencephaly with cyclopis (a case report). J Postgrad Med 1991;37:51-52

Abstract Views: 296

PDF Views: 0




  • Iniencephaly: A Case Report

Abstract Views: 296  |  PDF Views: 0

Authors

Saumya Shukla
Department of Pathology, Kasturba Medical College, Manipal University, Mangalore, India
Hema Kini
Department of Pathology, Kasturba Medical College, Manipal University, Mangalore, India

Abstract


Iniencephaly is an unusual malformation of variable incidence with involvement of the occiput (inion) and the brain. The features are: (1) Imperfect formation of the base of skull; (2) Rachischisis; (3) Retroflexion of the spine. We present a case report that illustrates the morphological features of iniencephaly. A multipara with 22 weeks gestation and history of gestational diabetes had a twin gestation with intrauterine death of both fetuses detected by ultrasound. An autopsy performed revealed one twin had features of iniencephaly while the other was morphologically normal. Iniencephaly is incompatible with life and its etiology is unknown requiring further experimental studies.

Keywords


Iniencephaly, Intrauterine Death

References