Open Access
Subscription Access
Preparation of Nanofibrous Mat Using Eco-Friendly, Biocompatible and Biodegradable Material
A novel blend of pectin/ chitosan (CS)/polyvinyl alcohol (PVA)has been prepared as a nanofibrous scaffold for skin tissue engineering and wound healing applications. Pectin has been used as an eco-friendly, non-toxic and water-soluble polymer to improve nanofibre properties. Pectin as a poly-anion polymer, in combination with chitosan polycationic polymers, creates a cross-linked poly-electrolyte complex with biocompatible properties. The CS/PVA solutions containing various concentrations of pectin are electrospun to form a 3D pectin/ CS/ PVA nano fibrous scaffold. Mechanical and antibacterial properties of the nanofibrous scaffolds are evaluated by various instrumental techniques, such as Attenuated Total Reflection-Fourier Transform Infrared, Scanning Electron Microscopy, nitrogen content and Differential Scanning Calorimetry. Mechanical properties are found to be improved and the strong antibacterial activity of the pectin/CS/PVA nano fibrous scaffold is confirmed against Escherichia coli, Staphylococcus aureus, Klebsiella and Candida albicans.
Keywords
Antibacterial Properties, Biocompatible Fibre, Biodegradable Fibre, Chitosan, Mechanical Properties, Nanofibrous, Pectin, Polyvinyl Alcohol.
User
Font Size
Information
- Hamidabadi G, Rezvani Z, Bojnordi M N, Shirinzadeh H, Seifalian A M, Joghataei M T, Razaghpour M, Alibakhshi A, Yazdanpanah A, Salimi M, Mozafari M, Urbanska A M, Reis R L, Kundu S C & Gholipourmalekabadi M, ACS Appl Mater Interfaces, 9 (2017) 11392.
- Kargozar S, Lotfibakhshaiesh N, Ai J, Mozafari M, Milan P B, Hamzehlou S, Barati M, Baino F, Hill R G & Joghataei M T, Acta Biomater, 58 (2017) 502.
- Aliramaji S, Zamanian A & Mozafari M, Mater Sci Eng C, 70 (2017) 736.
- Fischer K M, Morgan K Y, Hearon K, Sklaviadis D, Tochka Z L, Fenton O S, Anderson D C, Langer R & Freed L E, Adv Healthc Mater, 5 (2016) 813.
- Gholipourmalekabadi M, Zhao S, Harrison B S, Mozafari M & Seifalian A M, Trends Bio technol, 34 (2016) 1010.
- Alhosseini S N, Moztarzadeh F, Mozafari M, Asgari S, Dodel M, Samadikuchaksaraei A, Kargozar S & Jalali N, Int J Nanomedicine, 7 (2012) 25.
- Khademhosseini A & Langer R, Nat Protoc, 11(2016)1775.
- Langer R & Vacanti J, J Pediatr Surg, 51(2016) 8.
- Mohammadi M R, Nojoomi A, Mozafari M, Dubnika A, Inayathullah M & Rajadas J, J Mater Chem B, 5 (2017) 3995.
- Morgan K Y, Sklaviadis D, Tochka Z L, Fischer K M, Hearon K, Morgan T D, Langer R & Freed L E, Adv Funct Mater, 26 (2016) 5873.
- Mozafari M, Moztarzadeh F, Rabiee M, Azami M, Maleknia S, Tahriri M, Moztarzadeh, Z & Nezafati N, Ceram Int, 36 (2010)2431.
- Poursamar S A, Azami A & Mozafari M, Colloids Surf B Biointerfaces, 84 (2011)310.
- Rezvani Z, Venugopal J R, Urbanska A M, Mills D K, Ramakrishna S & Mozafari N, Nanomed Nanotechnol, 12(2016)2181.
- Sarem M, Moztarzadeh F & Mozafari M, Carbohydr Polym, 93 (2013)635.
- Vahid H, Masoud M, Daryoosh V & Lobat T, J Nano Sci Nano Technol, 14 (2014)522.
- Webber M J, Khan O F, Sydlik S A, Tang B C & Langer R, Ann Biomed Eng, 43 (2015) 641.
- Zia S, Mozafari M, Natasha G, Tan A, Cui Z & Seifalian A M, Crit Rev Biotechnol, 36 (2016) 705.
- Bhowmick S, Rother S, Zimmermann H, Lee P S, Moeller S, Schnabelrauch M, Koul V, Jordan R, Hintze V & Scharnweber D, Mater Sci Eng C, 79 (2017)15.
- Fu L, Xie J, Carlson M A & Reilly D A, MRS Commun, 7 (2017)361.
- Zhu C, Wang C, Chen R & Ru C, IFMBE Proceedings, EMBEC 2017 (NBC 2017), 2018, 1.
- Chandika P, Ko S C, Oh G W, Heo S Y, Nguyen V T, Jeon Y J, Lee B, Jang C H, Kim G H, Park W S, Chang W, Choi W & Jung W K, Int J Biol Macromol, 81 (2015)504.
- Gautam S, Chou C F, Dinda A K, Potdar P D & Mishra N C, Mater Sci Eng C, 34 (2014)402.
- Ghosal K, Manakhov A, Zajíčková L & Thomas S, AAPS Pharm Sci Tech, 18 (2017) 72.
- Han F, Dong Y, Su Z, Yin R, Song A & Li S, Int J Pharm, 476 (2014) 124.
- Ozpur M A, Guneren E, Canter H I, Karaaltin M V, Ovali E, Yogun F N, Baygol E G & Kaplan S, Plast Reconstr Surg, 137 (2016)134.
- Pezeshki-Modaress M, Mirzadeh H & Zandi M, Mater Sci Eng C,48 (2015)704.
- Ru C, Wang F, Pang M, Sun L, Chen R & Sun Y, ACS Appl Mater Interfaces, 7 (2015)10872.
- Vashisth P, Nikhil K, Roy P, Pruthi P A, Singh R P & Pruthi V, Carbohydr Polym, 136 (2016)851.
- Zhang W, Zhao L, Ma J, Wang X, Wang Y, Ran F, Wang Y, Ma H & Yu S, Fiber Polym, 18 (2017)922.
- Arkoun M, Daigle F, Heuzey M C & Ajji A, Food Sci Nutr, 5 (2017) 865.
- Prikhozhdenko ES, Lengert E V, Parakhonskiy B, Gorin DA, Sukhorukov GB & Yashchenok A M, Acta Phys Pol A, 129 (2016)247.
- Cao L, Zhang F, Wang Q & Wu X, Mater Sci Eng C, 79 (2017) 697.
- Ceylan Z, Sengor G F U, Sağdıç O & Yilmaz M T, LWT - Food Sci Technol, 79 (2017)367.
- Chen S, Cui S, Hu J, Zhou Y & Liu Y, Carbohydr Polym, 174 (2017) 591.
- Zhang X, Jia C, Qiao X, LiuT & Sun K, Polym Test, 62 (2017) 88.
- Gupta V K, Fakhri A, Agarwal S & Azad M, Int J Biol Macromol, 103 (2017)1.
- Jalaja K, Naskar D, Kundu S C & James N R, Carbohydr Polym, 136 (2016)1098.
- Rajendran D, Hussain A, Yip D, Parekh A, Shrirao A & Cho C H, J Biomed Mater Res, 105 (2017)2119.
- Karakas K, Celebioglu A, Celebi M, Uyar T & Zahmakiran M, Appl Catal B-Environ, 203 (2017)549.
- Razzaz A, Ghorban S, Hosayni L, Irani M & Aliabadi M, J Taiwan Inst Chem Eng, 58 (2016)333.
- Jhala D, Rather H & Vasita R, BiomaterSci, 4(2016) 1584.
- Khankhean A, Kuratsameethong W, Santibenchakul S, Laobuthee A, Sugimoto M, Srisawat N & Jamnongkan T, S Afr J Chem Eng, 37 (2021) 179.
- Ahire JJ, Robertson D D, Van Reenen A J & Dicks L M T, Mater Sci Eng C, 77 (2017) 27.
- Alavarse A C, Silva F W O, Colque J T, Silva V M, Prieto T, Venancio E C & Bonvent J J, Mater Sci Eng C, 77 (2017)271.
- Anjaneyulu U, Priyadarshini B, Grace A N & Vijaya Lakshmi U, J Solgel Sci Technol, 81 (2017) 750.
- El-Newehy M H, El-Naggar M E, Alotaiby S, El-Hamshary H, Moydeen M & Al-Deyab S, J Macromol Sci A, 53 (2016)566.
- Lin J H, Lin M C, Lee M. C, Lu CT, Huang C L & Lou C W, Influential factors on formation of nanofibers: Assessments of electrostatic spinning parameters. paper presented at the Symposium on Asia-Pacific Engineering and Technology Conference (APETC 2017), Kuala Lumpur, 25-26 May 2017.
- Kumar S, Rai P, Sharma J G, Sharma A & Malhotra B D, Adv Mater Technol, 1 (2016)1.
- Neugirg BR, Burgard M, Greiner A & Fery A, J Polym Sci Part B: Polym Phys, 54 (2016)2418.
- Qian Y, Qi M, Zheng L, King M W, Lv L & Ye F, Mater, 9 (2016) 1.
- Yan E, Cao M, Wang Y, Hao X, Pei S, Gao J, Wang Y, Zhang Z & Zhang D, Mater Sci Eng C, 58 (2016)1090.
- Zeng Q, Qin J, Yin X, Liu H, Zhu L, Dong W & Zhang S, J Appl Polym Sci, 133 (2016)1.
- Rezaee O, Chenari H M, Ghodsi F E & Ziyadi H, J Alloys Compd, 690 (2017)864.
- Vashisth P, Raghuwanshi N, Srivastava A K, Singh H, Nagar H & Pruthi V, Mater Sci Eng C, 71 (2017)611-619.
- Kim E & Kim J H, Int J Text Eng, 53 (2016)75.
- Majd S A, Khorasgani M R, Moshtaghian S J, Talebi A & Khezri M, Int J Biol Macromol, 92 (2016) 1162.
- Vega-Cázarez C A, López-Cervantes J, Sánchez-Machado D I, Madera-Santana T J, Soto-Cota A & Ramírez-Wong B, J Polym Environ, 26 (2018)946.
- Jamnongkan T, Wattanakornsiri A, Pansila P P, Migliaresi C & Kaewpirom S, Adv Mat Res, 463 (2012)734.
- Ando Y, Hagiwara S & Nabetani H, J Food Eng, 199 (2017)9.
- Cui S, Yao B, Sun X, Hu J, Zhou Y & Liu Y, Mater Sci Eng C, 59 (2016)885.
- Cui S, Yao B, Gao M, Sun X, Gou D, Hu J, Zhou Y & Liu Y, Carbohydr Polym, 157 (2017)766.
- Kastner H, Einhorn-Stoll U & Drusch S, Food Hydrocoll, 73 (2017) 13.
- Lin HY, Chen H H, Chang S H & Ni T S, J Biomater Sci Polym Ed, 24 (2013)470.
- Tripathi S, Mehrotra G K & Dutta P K, Carbohydr Polym, 79 (2010)711.
- Cui S, Sun X, Yao B, Peng X X, Zhang X T, Zhou Y F, Hu J L& Liu Y C, J Nano Sci Nano Technol, 17 (2017)681.
- Hocq L, Pelloux J & Lefebvre V, Trends Plant Sci, 22 (2017) 20.
- Liu S C, Li R, Tomasula P M, Sousa A M & Liu L, Food Sci Nutr, 7 (2016) 636.
- Kim Y, Williams M A, Luzio G A & Cameron R G, Food Hydrocoll, 69 (2017)422.
- Leśniewska J, Öhman D, Krzesłowska M, Kushwah S, Barciszewska-Pacak M, Kleczkowski LA, Sundberg B, Moritz T & Mellerowicz E J, Plant Physiol, 173 (2017)1409.
- Akhgari A & Hossein R M, Nanomed J, 3 (2016)43.
- Ndeh D, Rogowski A, Cartmell A, Luis A S, Baslé A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A & Terrapon N, Nature, 544 (2017)65.
- Shahidi S & Moazzenchi B, J Nat Fibers, 16 (2019)677.
- Shahidi S, Ghoranneviss M & Sharifi S D, J Fusion Energy, 33 (2014) 177.
- Guénin S, Hardouin J, Paynel F, Müller K, Mongelard G, Driouich A, Lerouge P, Kermode A R, Lehner A, Mollet J C, Pelloux J, Gutierrez L & Mareck A, J Exp Bot, 68 (2017)1083.
- Harholt J, Suttangkakul A & Scheller H V, Plant Physiol, 153 (2010)384.
- Peaucelle A, Braybrook S A, Le-Guillou L, Bron E, Kuhlemeier C & Höfte H, Curr Biol, 21 (2011) 1720.
- Ye X, ZhanY, Li T, Shi X, Deng H & Du Y, Int J Biol Macromol, 93 (2016)123.
Abstract Views: 136
PDF Views: 94