Indian Journal of Medicine and Healthcare

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Alterations in some Biochemical Indices of Hepatic Function in Tuberculosis Patients on Antituberclosis Therapy


Affiliations
1 Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria
2 Thank god medical Laboratories Ihiala, Anambra State, Nigeria
 

This study was to investigate the hepatic pathophysiology and biochemical changes during antituberclosis therapy. Among the intake 200 patients: 60 were on therapy, another 60 were not on therapy, while 80 were non tuberculosis patient. A comparative decrease in the level of total protein and albumin in tuberculosis patients were recorded while increase in Asparate Aminotransfarace (AST), Alanine Aminotransferace (ALT), and Alkaline Phosphatase (ALP) were observed in comparison with the control. On treatment with antituberclosis therapy, the hepatic involvements are transient.

Keywords

Biochemical Indices, Hepatic Pathophysiology, Antituberculosis Therapy
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  • Alterations in some Biochemical Indices of Hepatic Function in Tuberculosis Patients on Antituberclosis Therapy

Abstract Views: 578  |  PDF Views: 296

Authors

Nnodim Johnkennedy
Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria
Afolabi Emmanuel Abiodun
Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria
Udujih Hellen Ifeoma
Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria
Okorie Hope
Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria
Nwobodo Emmanuel Ikechukwu
Thank god medical Laboratories Ihiala, Anambra State, Nigeria
Nwadike Constance Nnedimma
Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, Nigeria

Abstract


This study was to investigate the hepatic pathophysiology and biochemical changes during antituberclosis therapy. Among the intake 200 patients: 60 were on therapy, another 60 were not on therapy, while 80 were non tuberculosis patient. A comparative decrease in the level of total protein and albumin in tuberculosis patients were recorded while increase in Asparate Aminotransfarace (AST), Alanine Aminotransferace (ALT), and Alkaline Phosphatase (ALP) were observed in comparison with the control. On treatment with antituberclosis therapy, the hepatic involvements are transient.

Keywords


Biochemical Indices, Hepatic Pathophysiology, Antituberculosis Therapy

References