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Anti-Antioxidant Activity of Alcoholic Extract of Nelumbo nucifera on Streptozotozin Induced Diabetic Albino Wistar Rats


Affiliations
1 Sughavazhvu Health Care, Thanjavur-613007, TN, India
2 Center for advanced research in Indian system of medicine, Sastra University, Thanjavur-614904. TN, India
 

The present study is to evaluate the in-vivo anti oxidant effect of hydro alcohol (50% aqueous ethanolic extract) extract of Nelumbo nucifera (G) flowers on streptozotocin-induced diabetes. Animals were induced for diabetes with streptozotocin (60 mg/kg of body weight, i.p.) and treated orally with hydro- alcoholic (50% aqueous ethanolic extract) extract of Nelumbo nucifera (G.) flowers in various doses (200 mg/kg and 400 mg/kg p.o). The effect of Nelumbo nucifera (G) flowers on diabetes was assessed from plasma glucose. At the end of the study, vital organs were dissected and estimated the parameters such as LPO, GSH, GPx and peroxidase. From the data obtained in this study it could be concluded that hydro alcoholic extract of Nelumbo nucifera (G) flowers seems to have potential value for the treatment of diabetic due to its Anti oxidant activity.

Keywords

Anti Diabetic, Anti-oxidants,Nelumbo Nucifera
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  • Anti-Antioxidant Activity of Alcoholic Extract of Nelumbo nucifera on Streptozotozin Induced Diabetic Albino Wistar Rats

Abstract Views: 565  |  PDF Views: 509

Authors

P. Manimekalai
Sughavazhvu Health Care, Thanjavur-613007, TN, India
C. Davidraj
Center for advanced research in Indian system of medicine, Sastra University, Thanjavur-614904. TN, India
R. Dhanalakshmi
Center for advanced research in Indian system of medicine, Sastra University, Thanjavur-614904. TN, India
B. Sudhakar
Center for advanced research in Indian system of medicine, Sastra University, Thanjavur-614904. TN, India

Abstract


The present study is to evaluate the in-vivo anti oxidant effect of hydro alcohol (50% aqueous ethanolic extract) extract of Nelumbo nucifera (G) flowers on streptozotocin-induced diabetes. Animals were induced for diabetes with streptozotocin (60 mg/kg of body weight, i.p.) and treated orally with hydro- alcoholic (50% aqueous ethanolic extract) extract of Nelumbo nucifera (G.) flowers in various doses (200 mg/kg and 400 mg/kg p.o). The effect of Nelumbo nucifera (G) flowers on diabetes was assessed from plasma glucose. At the end of the study, vital organs were dissected and estimated the parameters such as LPO, GSH, GPx and peroxidase. From the data obtained in this study it could be concluded that hydro alcoholic extract of Nelumbo nucifera (G) flowers seems to have potential value for the treatment of diabetic due to its Anti oxidant activity.

Keywords


Anti Diabetic, Anti-oxidants,Nelumbo Nucifera

References