Indian Journal of NanoScience

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Antimicrobial Activity of Synthesized Silver Nanoparticles and Phytochemical Screening of the Aqueous Extract of Mussaenda ferruginea


Affiliations
1 Department of Applied Sciences, PNG University of Technology, LAE, Papua New Guinea
2 Deptartment of Medical Biochemistry, University of Madras, Taramani Campus, Chennai600113, Chennai, India
3 Dept of Biochemistry, JBAS College for Women, Teynampet, Chennai-600018, India
 

Background/Objectives: Mussaenda ferruginea is used as a traditional medicine around many parts of Papua New Guinea. It is used traditionally in the treatment of malaria and fever. The main aim of this study was to evaluate the compatibility of M. ferruginea in synthesizing silver nanoparticles and determine their antimicrobial activity.

Methods/Statistical analysis: 3mM and 6mM concentration of silver nanoparticles were prepared and checked for the antimicrobial activity using agar paper disc diffusion assay and measuring the zone of inhibition against 14 microorganisms. Also the photochemical screening was carried out for the aqueous extract of the plant.

Findings: All the microorganisms used were found to be highly susceptible to the synthesized silver nanoparticles. Phytochemical screening of M. ferruginea reveals the presence of alkaloids, glycosides, terpenoids, reducing sugars, saponins and phenolic compounds.

Improvements/Application: All the microorganisms are susceptible to silver nanoparticles but are resistant to the plant extract.


Keywords

Mussaenda ferruginea, Antimicrobial Activities, Agar well Diffusion Assay, Phytochemical Screening.
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  • Antimicrobial Activity of Synthesized Silver Nanoparticles and Phytochemical Screening of the Aqueous Extract of Mussaenda ferruginea

Abstract Views: 372  |  PDF Views: 182

Authors

S. Gopalakrishnan
Department of Applied Sciences, PNG University of Technology, LAE, Papua New Guinea
S. Yamini Sudha Lakshmi
Deptartment of Medical Biochemistry, University of Madras, Taramani Campus, Chennai600113, Chennai, India
Fouzia Banu
Dept of Biochemistry, JBAS College for Women, Teynampet, Chennai-600018, India

Abstract


Background/Objectives: Mussaenda ferruginea is used as a traditional medicine around many parts of Papua New Guinea. It is used traditionally in the treatment of malaria and fever. The main aim of this study was to evaluate the compatibility of M. ferruginea in synthesizing silver nanoparticles and determine their antimicrobial activity.

Methods/Statistical analysis: 3mM and 6mM concentration of silver nanoparticles were prepared and checked for the antimicrobial activity using agar paper disc diffusion assay and measuring the zone of inhibition against 14 microorganisms. Also the photochemical screening was carried out for the aqueous extract of the plant.

Findings: All the microorganisms used were found to be highly susceptible to the synthesized silver nanoparticles. Phytochemical screening of M. ferruginea reveals the presence of alkaloids, glycosides, terpenoids, reducing sugars, saponins and phenolic compounds.

Improvements/Application: All the microorganisms are susceptible to silver nanoparticles but are resistant to the plant extract.


Keywords


Mussaenda ferruginea, Antimicrobial Activities, Agar well Diffusion Assay, Phytochemical Screening.