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A Study of Management of Periodontal Osseous Defects with Xenograft and Bioresorbable Membrane
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Recent research has focused upon use of bone substitutes in combination with the GTR barriers for better clinical outcomes of periodontal regenerative procedures.The purpose of this study was to evaluate the efficacy of bovine derived xenograft (Bio-Oss) and bioresorbable GTR membrane (Atrisorb) in interproximal vertical Defects.
Two systemically healthy patients (1 male,1 female) were selected with 12 sites each. Sites were assigned randomly into control (flap debridement Plus Bio-Oss)and experimental( flap debridement plus Bio-Oss and Atrisorb). Clinical measurements included plaque index (PI), gingival index (GI), probing pocket depth (PPD), Clinical attachment level (CAL), gingival margin position (GMP). Statistical Analysis was performed using the paired and unpaired 't' tests.
In the results, the control and experimental group showed statistically highly significant (p<0.001) Changes in GI, PPD and CAL 9 months post surgery. Between the groups statistical significance was not found in all clinical Parameters. Radiographic measurements showed a statistically highly significant Amount of defect fill in individual in each group and between the groups.
In this study the combined use of GTR barrier and bone graft did not prove beneficial Over the bone graft alone for the clinical outcome of interproximal vertical defect treatment.
Keywords
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