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Prasad, B K
- Study of Diurnal Variation of Pulmonary Function Test
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Authors
B K Prasad
1,
B L Ashika
2
Affiliations
1 Dept of Physiology, SSIMS & RC Davangere
2 II Phase MBBS, SSIMS & RC Davangere, Karnataka
1 Dept of Physiology, SSIMS & RC Davangere
2 II Phase MBBS, SSIMS & RC Davangere, Karnataka
Source
Indian Journal of Public Health Research & Development, Vol 4, No 2 (2013), Pagination: 173-178Abstract
Pulmonary function has circadian rhythm in humans proven in diseased in conditions. These variations will contribute to better understanding the relationship between biorhythms and lung physiology for better management of pulmonary diseases.To study PFT in medical students during different time of the day and to study whether there is diurnal variation in PFT .The I MBBS students chosen as subjects were apparently normal and non-smokers. The study group included 113 students. They underwent PFT during different time of the day, i.e., at 6am, 11am, 4pm and 9pm. PFT was done using computerized Spirometer and the parameters studied were FEV1, FVC, FEV1/FVC, PEF, FEF25- 75% and FEF.2-1.2L. The data was tabulated and statistically analyzed. There were changes in all the PFT parameters recorded during different time of the same day. Mean of FEV1 and FVC were highest in the recording taken at 9:00pm. % change noted was 1.74% and 1.32% respectively, when compared to the recording at 6:00am. Mean of FEV1/FVC ratio also showed diurnal rhythm with highest % at 11:00am and lowest % at 6:00am. The % change noted was 0.76%. Mean of PEFR, FEF25-75% and FEF0.2-1.2L showed diurnal rhythm. They were high in the recording done at 4:00pm and low in the recording done at 6:00am. % change noted in PEFR, FEF25-75% and FEF.2-1.2L were 2.25%, 3.66% and 2.08% respectively. % change noted for each parameter was statistically not significant. The diurnal variation in PFT parameters is noted in healthy subjects. The % change noted is minimal in young healthy individuals. This diurnal rhythm amplitude increase in asthma and bronchitis patients.Keywords
PFT, Computerized Spirometer, Diurnal Variation
References
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- Study of Effect of Smoking on Auditory Acuity
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Authors
Affiliations
1 Dept. of Physiology, SSIMS & RC NH-4 Bypass Road, Davangere, Karnataka, IN
2 Dept of Physiology, SDUMC, Kolar, Karnataka, IN
1 Dept. of Physiology, SSIMS & RC NH-4 Bypass Road, Davangere, Karnataka, IN
2 Dept of Physiology, SDUMC, Kolar, Karnataka, IN
Source
Indian Journal of Public Health Research & Development, Vol 4, No 4 (2013), Pagination: 162-167Abstract
Background: The relationship between smoking and hearing loss has been debated. Smoking appears to have an effect on auditory acuity and the proposed mechanisms are the direct oxidative damage on cochlea caused by toxic substances inhaled with the cigarette smoke or to the acceleration of the atherosclerotic process in the cochlear artery.
Objectives: To record the auditory thresholds of age matched male smokers and non-smokers of age group 20-40 yrs, using pure tone audiometer and compare the auditory thresholds between the groups.
Method: Age matched male 100 smokers and 100 non-smokers were subjected to pure tone audiometric assessment. The smoking history in terms of pack-years was also noted. The data was statistically analyzed.
Results: Smokers group were significantly hearing impaired than the non-smokers group. The hearing impairment was noted at all frequencies tested. Higher frequencies were more affected than the lower frequencies. The auditory thresholds of smokers had significant positive correlation with smoking history, indicating that auditory thresholds rise as the number of pack-years increase.
Conclusion: Smoking causes hearing impairment. The higher frequencies are more affected. The auditory thresholds rise as the number of pack-years increase.
Keywords
Smoking, Hearing Loss, Pure Tone Audiogram, Auditory Thresholds, Sensorineural Hearing LossReferences
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