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Cinthura, C.
- COX2 Inhibitory activity of Abutilon indicum-In Invitro Study
Authors
1 Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
3 Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
4 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3523-3526Abstract
Aim: To analyse the COX2 inhibitory activity of Abutilon indicum.
Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum.
Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms - COX-1 and COX-2. Abutilon indicum ,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial.
Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits