Indian Journal of Public Health Research & Development

Ramachandran Tamilselvi ¹, Malarvizhi Dakshinamoorthy ², Karthick Arumugam ², Bhaskaran Sathyapriya ³, Purushothaman Lakshmanan ⁴

Affiliations
1 Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education & Research, IN
2 Department of Conservative Dentistry & Endodontics, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education & Research, IN
3 Department of Anatomy, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education & Research, IN
4 Apollo Hospitals and Apollo White Dental & Sree Venkateshwara Dental College & Hosapital, Chennai, Tamil Nadu, IN

Abstract

The objective of this invitro study was to investigate, whether the remineralization potential of conventional GIC in human dentin could be improved by combining with CPP - ACP and nano hydroxyapatite. Class I cavities were prepared in sound human extracted third molars and they were randomly assigned to 3 groups according to the restorative materials. Group I: Conventional GIC, Group II:Conventional GIC and CPP-ACPand Group III: Conventional GIC powder & Nano hydroxy apatite. The samples were subjected to remineralizationand demineralization cycles for period of 2 weeks. Energy dispersive X-ray analysis was used to evaluate the remineralization. The elemental compositions were analyzed using One way ANOVA, Post Hoc and Mann Whitney tests. The calcium and phosphate concentration were statistically significantly greater in Group III than Group I and II (P<0.05).Nanohydroxy apatite with GIC remineralized the demineralized dentin almost equal to normal dentin.

Clinical Relevance: GIC with nanohydroxy apatite might be superior restorative/base with an improved remineralization potential of dentin.

Keywords

GIC, DENTIN, HYDROXYAPATITE.

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Tamilselvi Ramachandran ¹, Malarvizhi Dakshinamoorthy ², Venkatesh Alagarsamy ³, Karthick Arumugam ²

Affiliations
1 Reader, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, IN
2 Associate Professor, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, IN
3 Professor, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, IN

Abstract

Dental caries is an infectious microbiologic disease causing localized dissolution and destruction of the calcified tissue. It is caused by host, agent, and environmental factors. The development and progression of dental caries mainly depends on time factor. The main pathogenic species involved in the initiation and development of dental caries are S. mutans, Lactobacillus acidophilus and Actinomyces viscosus. The prevention and control of dental caries plays a major role in the status of public health. Caries vaccines have been developed to prevent and protect against dental caries. Various types of vaccines are being developed at research centres, with some kind of caries vaccines being considered to diminish or prevent dental caries among the children and adults.

Keywords

Dental Caries, Caries Caccine, Glucosyl Transferase, Mutans Streptococci.

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