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Authors
Affiliations
1 Lecturer, Department of Orthodontic, Pedodontic and Preventive Dentistry, College of
Dentistry, Iraq, Mustansiyriah University, IQ
2 Assistant Professor, Department of Orthodontic, Pedodontic and Preventive Dentistry, College of Dentistry, Iraq, Mustansiyriah University, IQ
3 Assistant Lecturer, Department of Orthodontic, Pedodontic and Preventive Dentistry, Dentistry Department, Dijlah University, IQ
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 2927-2930
Abstract
Background: Saliva has been suggested as a non-invasive diagnostic fluid that may be used in the diagnosis of oral and systemic diseases. The salivary levels of IL-17 could be used as a substitute to distinguish periodontal healthy from periodontitis subjects. Therefore, the goal of the present investigation was to determine if the levels of IL-17 in saliva would differ between a group of periodontal healthy and periodontitis subjects. Correlations between the concentration of IL-17 and clinical parameters of periodontal disease were also examined.
Subjects and Method: Unstimulated saliva was collected from each individual (24 patients with periodontitis and 24 healthy age-and gender-matched individuals as control group). Salivary interleukin 17 level was evaluated for both groups using enzyme-Linked Immuno-sorbent assay technique.
Results: Mean values of IL-17 levels were highly significantly increased in patients with chronic periodontitis patients as compared to healthy control subjects.
Conclusion: Interleukin 17 has special importance could be used as a positive predictive factor for prediction and diagnosis of periodontitis.
Keywords
IL-17, ELISA, Periodontitis, Saliva, Biomarkers.
