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Authors
Affiliations
1 Pathology, Medical College & Hospital Ghaziabad, IN
2 Ophthalmology, Medical College & Hospital Ghaziabad, IN
3 Obstetrics and Gynecology, Medical College & Hospital Ghaziabad, IN
Source
Indian Journal of Public Health Research & Development, Vol 5, No 3 (2014), Pagination: 131-136
Abstract
Introduction: Anti-cardiolipin antibodies are autoantibodies which may be associated with unexplained recurrent abortions.
Aims&Objectives: To evaluate the role of anti-cardiolipin antibodies in unexplained, recurrent abortions.
Materials&Method: A cohort of 28 females with recurrent spontaneous abortions were studied for anti-cardiolipin antibodies by ELISA. 20 normal fertile age matched females served as controls.
Result: 25% cohorts were positive for anti-cardiolipin antibodies. They also had increased frequency of the antibody (35%) as compared to primary aborters (12.5%). All healthy controls were negative. All positive cases were either moderately or weakly positive for the antibody by ELISA.
Conclusion: Anti-cardiolipin antibodies may be associated with spontaneous recurrent abortion. It should be tested in all cases of recurrent miscarriages.
Keywords
APA (anti-phospholipid Antibodies), AC Lab (anti-cardiolipin Antibodies), ELISA (enzyme Linked Immunosorbant Assay), APLS (anti-phospholipid Syndrome).
