Objective: To investigate the effect adding mobilization with movement (MWM) technique to the traditional physical therapy program of knee osteoarthritis. Design: Randomized controlled pilot study. Setting: Outpatient clinic Faculty of physical therapy, Cairo University. Subjects: Thirty patients with knee OA, participated in the study with ages ranged from 30-60 years. Intervention: They were randomly assigned into two groups. Group (A) consisted of fifteen patients who received a traditional physiotherapy program, Group (B) consisted of fifteen patients who received traditional physical therapy program +MWM. Treatment for both groups was three times a week for four weeks. Main measures: The assessment was conducted at the beginning of first session and at the end of last session. Pain intensity was measured by the visual analogue scale. WOMAC was used to assess patient. ROM of knee joint was assessed using The Guymon electrogoniometer. Results: For pain intensity and knee range of motion, there were significant differences between groups in favor of the group B with p< 0.05. For disability, there was no significant difference between groups. Conclusions: MWM should be added to the traditional program for knee osteoarthritis.