International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN)

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Antimicrobial Activity of Silver Nanoparticles Prepared Under an Ultrasonic Field


Affiliations
1 Department of Physics, Mother Teresa Women’s University, Kodaikanal – 624101, Tamil Nadu, India
2 Department of Physics, Mother Teresa Women’s University, Kodaikanal – 624101, Tamil Nadu,, India
3 Department of Zoology, University of Madras, Guindy Campus, Chennai- 600025, Tamil Nadu,, India
 

Nanotechnology has great promise for improving the therapeutic potential of medicinal molecules and related agents. In this study, silver nanoparticles of different sizes were synthesized in an ultrasonic field using the chemical reduction method with sodium borohydride as a reducingagent. The size effect of silver nanoparticles on antimicrobial activity were tested against the microorganisms Staphylococcus aureus (MTCC No. 96), Bacillus subtilis (MTCC No. 441), Streptococcus mutans (MTCC No. 497), Escherichia coli (MTCC No. 739) and Pseudomonasaeruginosa (MTCC No. 1934). The results shows that B.subtilis, and E. coli were more sensitive to silver nanoparticles and its size, indicating the superior antimicrobial efficacy of silver nanoparticles.

Keywords

Optical absorption; silver NP; particle size analyzer; antimicrobial activity; size effect.
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  • Antimicrobial Activity of Silver Nanoparticles Prepared Under an Ultrasonic Field

Abstract Views: 66  |  PDF Views: 57

Authors

M. Umadevi
Department of Physics, Mother Teresa Women’s University, Kodaikanal – 624101, Tamil Nadu, India
T. Rani
Department of Physics, Mother Teresa Women’s University, Kodaikanal – 624101, Tamil Nadu,, India
T. TBalakrishnan
Department of Zoology, University of Madras, Guindy Campus, Chennai- 600025, Tamil Nadu,, India
R. Ramanibai
Department of Zoology, University of Madras, Guindy Campus, Chennai- 600025, Tamil Nadu,, India

Abstract


Nanotechnology has great promise for improving the therapeutic potential of medicinal molecules and related agents. In this study, silver nanoparticles of different sizes were synthesized in an ultrasonic field using the chemical reduction method with sodium borohydride as a reducingagent. The size effect of silver nanoparticles on antimicrobial activity were tested against the microorganisms Staphylococcus aureus (MTCC No. 96), Bacillus subtilis (MTCC No. 441), Streptococcus mutans (MTCC No. 497), Escherichia coli (MTCC No. 739) and Pseudomonasaeruginosa (MTCC No. 1934). The results shows that B.subtilis, and E. coli were more sensitive to silver nanoparticles and its size, indicating the superior antimicrobial efficacy of silver nanoparticles.

Keywords


Optical absorption; silver NP; particle size analyzer; antimicrobial activity; size effect.

References