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Sharma, Amrish
- Hypolipidemic Activity of Leaves and Fruits of Ficus bengalensis in Alloxan Induced Diabetic Rats
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Authors
Affiliations
1 People’s Hospital, PCMS Campus, HIG C-4, Bhanpur Road, Bhopal-462 037 (M.P), IN
2 People’s Institute of Pharmacy and Research Centre, Bhopal Bhanpur Road, Bhopal-462 037 (M.P.), IN
1 People’s Hospital, PCMS Campus, HIG C-4, Bhanpur Road, Bhopal-462 037 (M.P), IN
2 People’s Institute of Pharmacy and Research Centre, Bhopal Bhanpur Road, Bhopal-462 037 (M.P.), IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 293-296Abstract
Diabetes mellitus is a metabolic disorder and associated with many other metabolic functional alterations. The bark of Ficus bengalensis and other plants are reported as antidiabeticand hypolipidemic due to presence of flavonoids and sterols. Based on literature survey, tribal information and chemical constituents, the present study is undertaken to observe the hypolipidemic potential of leaves and fruits of Ficus bengalensis because they also contain the same active constituents. Hence, the leaves and fruits may have same activity like bark. To study the object, different doses of ethanolic extract of leaves and fruits of Ficus bengalensis was given to alloxan induced diabetic rats.Keywords
Ficus bengalensis, Hypolipidemic, Antidiabetic, Alloxan, Flavonoids, Sterol.- RP HPLC Determination of Amlodipine in its Pharmaceutical Dosage Forms
Abstract Views :137 |
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Authors
Affiliations
1 People’s Institute of Pharmacy and Research Centre, Bhanpur, Bhopal-462037 (M.P.), IN
1 People’s Institute of Pharmacy and Research Centre, Bhanpur, Bhopal-462037 (M.P.), IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 129-131Abstract
A new and simple reverse phase HPLC method was developed for the determination of amlodipine in its pharmaceutical dosage form. The mobile phase used acetonitrile, methanol, KH2PO4 was in the ratio of 250: 250: 500. Buffer solution was prepared by dissolving 0.05 m KH2PO4+0.1% H3PO4 adjunct with triethylamine. The separation was achieved on hypersil C-18 column, phenomenex Gemini (250×4.6 mm) and 5 μ particle size with rheodyne injector. The flow rate was 1ml/min and UV detection at 238 nm. The retention time for amlodipine was 9 min. The linearity coefficient of Amlodipine was 0.99% and the percentage recoveries for amlopdipine was 100.02% respectively. The proposed method was accurate, precise and linear within the desired range. This method can be successfully employed for the quantitative analysis of amlodipine.Keywords
RP HPLC, Validation, Atenolol.- RP-HPLC Determination of Atenolol in its Pharmaceutical Dosage Forms
Abstract Views :179 |
PDF Views:0
Authors
Affiliations
1 People’s Institute of Pharmacy and Research Centre, Bhanpur, Bhopal-462037 (M.P.), IN
1 People’s Institute of Pharmacy and Research Centre, Bhanpur, Bhopal-462037 (M.P.), IN