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Praveen, B.
- Comparative Study of Various Mycotoxins against few Bacterial Test Organisms
Abstract Views :182 |
PDF Views:71
Authors
Bisht Satpal Singh
1,
B. Praveen
1,
Panda Amrita
1,
Behera Santosh
1,
Panda Koustava Kumar
1,
Rojita Mishra
1,
Patro Subhra Kanta
1
Affiliations
1 Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, IN
1 Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, IN
Source
Journal of Pharmaceutical Research, Vol 10, No 3 (2011), Pagination: 116-119Abstract
The present investigation is an attempt to isolate various fungal sources producing mycotoxins from air and soil. Mycotoxins produced by various fungal strains are aflatoxin, gliotoxin, Penicillin, Patulin, Terrecyclic acid, Deoxynivalenol, Malformin, Fumonisin and Trichorzin. The antibacterial potential of the mycotoxins was tested against various test organisms and it was found that the aflatoxin is effective against Micrococcus luteus (MTCC No. 1538) and Pseudomonas sp. (MTCC No. 7021), in case of Gliotoxin it was observed that it has a very good antibacterial property against E. coli (MTCC No. 40), penicillin was found equally good for Micrococcus luteus (MTCC No. 1538) E. coli (MTCC No. 40). Antimicrobial activity of Patulin was observed highest against Micrococcus luteus (MTCC No. 1538), Proteus sp. (MTCC No. 426) was found to be more sensitive to Terrecyclic acid, Micrococcus sp. (MTCC No. 7527) was found most sensitive against Deoxynivalenol generating zone of inhibition 32.66 mm in case of crude and 47.66 mm in case of purified extract and Malformin was found highly effective against Proteus sp. (MTCC No. 426). The Fumonisin and Trichorzin were found as a candidate mycotoxin against Bacillus megaterium (MTCC No. 2412), Micrococcus sp. (MTCC No. 7527), Pseudomonas aeruginosa (MTCC No. 424) respectively.Keywords
Mycotoxins, Zone of Inhibition, Antibacterial Activity.Full Text
- Therapeutic Efficiency of Leucas aspera (Lamiaceae) on Lead Acetate Induced Nephrotoxicity and Oxidative Stress in Male Wistar Rat
Abstract Views :194 |
PDF Views:0
Authors
Affiliations
1 Dept. of Pharmaceutical Analysis and Quality Assurance, Raghavendra College of Pharmacy, Anantapur, A.P., IN
2 Dept. of Pharmacology, Sri Venkateshwara University, Tirupathi, Andhra Pradesh, IN
3 Dept. of Pharmaceutical Analysis and Quality Assurance, Alliance College of Pharmacy, Hyderabad, A.P., IN
1 Dept. of Pharmaceutical Analysis and Quality Assurance, Raghavendra College of Pharmacy, Anantapur, A.P., IN
2 Dept. of Pharmacology, Sri Venkateshwara University, Tirupathi, Andhra Pradesh, IN
3 Dept. of Pharmaceutical Analysis and Quality Assurance, Alliance College of Pharmacy, Hyderabad, A.P., IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 10 (2011), Pagination: 1515-1519Abstract
Leucas aspera (Lamiaceae) is a herbaceous medicinal plant used to treat inflammation, skin infections etc in India and other Asian countries. Lead acetate, a common contaminate in water causes liver and kidney necrosis in man and animals. The aim of the present study is to investigate the nephroprotective and antioxidant activities of the methanol extract of L. aspera in three dose levels of 50mg/kg, 100mg/kg and 2000 mg/kg respectively on lead acetate induced toxicity in rats and comparing it with the marketed formulation of Silymarin. Biochemical studies show that there is an reduction in the levels of super oxide dismutase, reduced glutathione, catalase and total proteins in Lead acetate induced groups. These values are retrieved significantly by treatment with L. aspera extracts at three different doses. Apart from these, histopathological changes also reveal the protective nature of the L. aspera extract against lead acetate induced necrotic damage of renal tissues. In conclusion, these data suggest that the methanolic extract of L.aspera can prevent renal damage from lead acetate induced nephrotoxicity in rats and it is likely to be mediated through its antioxidant activities.
Keywords
Lead Acetate, Nephroprotectivity, Antioxidant, Leucas aspera.
- Biofertilizers - A Noble Technology for Sustainable Agriculture
Abstract Views :250 |
PDF Views:6
Authors
Affiliations
1 Department of Plant Pathology, Centurion University of Technology and Management, Parlakhemundhi (Odisha), IN
1 Department of Plant Pathology, Centurion University of Technology and Management, Parlakhemundhi (Odisha), IN
Source
Asian Journal of Bio Science, Vol 13, No 1 (2018), Pagination: 50-53Abstract
Green revolution played a major role in reducing food crisis by introducing and developing high yielding varieties (HYV). Since, these varieties are highly fertilizer responsive, the usage of fertilizers increased to maximum extent with an aim to get higher productivity. Indiscriminate use of chemical fertilizers, pesticides and other highly productive systems had a serious effect on our environment. To attain sustainable production from soil reduced use of chemical fertilizers by substituting it with some new technologies is highly required. The bio fertilizer is one such technology which is gaining importance in integrated plant nutrient system as it maintains soil health, substitutes the chemical fertilizers thereby reducing their usage, increases microbial population of soil and minimizes environmental pollution.Keywords
Biofertilizers, Chemical Fertilizers, Environmental Pollution, High Yielding Varieties, Mass Production.References
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