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R, Chaudhary
- A Study of Fine Needle Aspiration Cytology of Breast Lesions in Females with Special Reference to IAC Standardized Reporting at a Tertiary Care Centre
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Authors
Affiliations
1 Associate Professor, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
2 Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
3 2Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
1 Associate Professor, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
2 Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
3 2Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, IN
Source
MVP Journal of Medical Sciences, Vol 8, No 1 (2021), Pagination: 8-15Abstract
Background: Carcinoma of the breast is one of commonest carcinomas found in Indian women and also around the world. Fine Needle Aspiration Cytology (FNAC), a quick, cost effective and patient compliant procedure, can give an adequate diagnosis to rule out at best the difference between a benign and malignant breast lump. The International Academy of Cytology (IAC) has developed a process for Fine-Needle Aspiration Cytology (FNAC) reporting that is thorough and standardized. C1 to C5 are the categories for breast lesions. Methods: A total of 166 breast FNACs were performed over a period of 2.5 years after fulfilling the inclusion and exclusion criteria and the aspirates were stained by Hematoxylin and Eosin stains and the stained slides were studied and diagnosis was made accordingly. The patients were classified using the IAC classification system that relies on their cytomorphological characteristics. Results: Out of 166 cases, 136 were neoplastic, 6 non-neoplastic and 24 cases were inadequate to opine. Of the 136 neoplastic cases, 89 cases (53.61%) were diagnosed as fibroadenoma and 19 cases (11.44%) were diagnosed as duct carcinoma. Conclusion: The fine needle aspiration cytology is a critical diagnostic tool in the management of patients with breast lump. It is an easy, reliable, patient friendly, repeatable and simple diagnostic test. FNAC can have a very high diagnostic accuracy when performed by experts.Keywords
Breast Lesion, Duct Carcinoma, Fibroadenoma, IAC Classification, FNACFull Text
References
- Malvia S, Bagadi SA, Uma SD, Saxena S. Epidemiology of breast cancer in Indian women. Asia-Pacific Journal of Clinical Oncology. 2017; 13:1–6. https://doi.org/10.1111/ ajco.12661. PMid:28181405
- Rupom TU, Choudhary T, Banu SG. Study of fine needle aspiration cytology of breast lumps: Correlation of cytologically malignant cases with their histological findings. Bangabandhu Sheikh Mujib Medical University Journal. 2011; 4(2):60–4. https://doi.org/10.3329/bsmmuj.v4i2.8631
- Khemka A, Chakrabarti N, Shah S, Patel V. Palpable breast lumps; Fine-needle aspiration cytology versus histopathology: A correlation of diagnostic accuracy. The Internet Journal of Surgery. 2009; 18(1). https://doi.org/10.5580/1ffb
- Orell SR, Sterret GF. Fine needle aspiration cytology, Elsevier, 3rd edition.
- Rosai J. Rosai and Ackerman’s surgical pathology, Elsevier 10th edition.
- Muddegowda PH, Lingegowda JB, Kurpad R, Konapur PG, Shivarudrappa AS, Subramaniam PM. The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation. Journal of Cytology. 2011; 28 (1):13-18. https://doi.org/10.4103/0970-9371.76942. PMid:21552401. PMCid:PMC3083528
- Ljung BM, Drejet A, Chiampi N, Jeffrey J, Goodson WH, Chew K, et al. Diagnostic accuracy of FNAB is determined by physician training in sampling technique. Cancer Cytopathology. 2001; 93:263–8. https://doi.org/10.1002/ cncr.9040. PMid:11507700
- Andrew SF, Fernando S, Philippe V. IAC Standardized reporting of breast fine-needle aspiration biopsy cytology. Acta Cytologica. 2017; 61:3–6. https://doi. org/10.1159/000450880. PMid:27806362
- Royal College of Australasia (RCPA): Structured pathology reporting of cancer [Internet]. [cited on 2016 Oct 31]. Available from: https://www.rcpa.edu.au/Health-Care
- International Confederation Cancer Reporting (ICCR) [Internet]. [cited on 2016 Oct 31]. Available from: https:// www.iccr-cancer.org
- Pal S, Gupta ML. Correlation between cytological and histological grading of breast cancer and its role in prognosis. Journal of Cytology. 2016; 33:182–6. https:// doi.org/10.4103/0970-9371.190449. PMid:28028331. PMCid:PMC5156979
- Oluwole SF, Freeman HP. Analysis of benign breast lesions in blacks. The American Journal of Surgery. 1979 Jun; 137(6):786–9. https://doi.org/10.1016/0002- 9610(79)90094-1
- Khanna R, Khanna S, Chaturvedi S, Arya NC. Spectrum of breast disease in young females: A retrospective study of 1315 patients. Indian Journal of Pathology and Microbiology. 1998 Oct; 41(4):397-401.
- Ochicha O, Edino ST, Mohammad AZ, Amin SN. Benign breast lesions in Kano. Nigerian Journal of Surgical Research. 2002; 4(1–2):1–5. https://doi.org/10.4314/njsr. v4i1.12162
- Malik R, Bharadwaj VK. Breast lesions in young females – A 20-year study for significance of early recognition. Indian Journal of Pathology and Microbiology. 2003 Oct; 46(4):559–62.
- Singh R, Satish A, Sharma M, et al. Spectrum of male breast lesions diagnosed by fine needle aspiration cytology: A 5-year experience at a tertiary care rural hospital in central India. Diagnostic Cytopathology. 2012; 40:113–7. https:// doi.org/10.1002/dc.21507. PMid:22246926
- Bansal C, Pujani M, Sharma KL, Srivastava AN, Singh US. Grading systems in the cytological diagnosis of breast cancer: A review. Journal of Cancer Research and Therapeutics. 2014; 10:839–45. https://doi.org/10.4103/0973-1482. 140979. PMid:25579516
- Silverman JF, Elsheikh TM, Singh HK. The role of fine needle aspiration cytology of the breast in the core biopsy era. Pathology Case Reviews. 2007; 12:44-8. https://doi. org/10.1097/01.pcr.0000252861.12112.19
- Kothari K, Tummidi S, Agnihotri M, Sathe P, Naik L. This ‘Rose’ Has no Thorns-Diagnostic Utility of ‘Rapid On-Site Evaluation’ (ROSE) in fine needle aspiration cytology? Indian Journal of Surgical Oncology. 2019. https:// doiorg/101007/s13193-019-00981-y.
- Schmitt F, Vielh P. FNAC samples: A good source of material to evaluate biomarkers in breast cancer. Histopathology. 2014; 64:971–80.
- Joan C, Aylin S. fine needle aspiration cytology. Elsevier: Toronto; 2012. pp. 156–209.
- Field AS, Zarka MA. Breast. In: Field AS, Zarka MA, editors. Practical Cytopathology: A diagnostic approach to fine needle aspiration biopsy. 5. Amsterdam: Elsevier; 2017.
- Sinha SK, Sinha N, Bandyopadhyay R, Mondal SK. Robinson’s cytological grading on aspirates of breast carcinoma: Correlation with Bloom Richardson’s histological grading. Journal of Cytology. 2009; 26:140–3. https:// doi.org/10.4103/0970-9371.62182. PMid:21938177. PMCid:PMC3167998
- Robles-Frías A, González-Cámpora R, Martínez-Parra D, Robles-Frías MJ, Vázquez-Cerezuela T, Otal-Salaverri C, et al. Robinson cytologic grading ofinvasive ductal breast carcinoma: Correlation with histologic grading and regional lymph node metastasis. Acta Cytologica. 2005; 49:149–53. https://doi.org/10.1159/000326123. PMid:15839618
- Meena SP, Deepika KH, Joshi N. A comparative and evaluative study of cytological and histological grading system profile in malignant neoplasm of breast – An important prognostic factor. Indian Journal of Pathology. 2006; 49:199–202.
- Rekha TS, Nandini NM, Dhar M. Validity of different cytological grading systems of breast carcinoma – A hospital- based study in South India. Asian Pacific Journal of Cancer Prevention. 2011; 12:3013–6.